INT90590

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Context Info
Confidence 0.77
First Reported 2000
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.01
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Spink1)
Spink1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 11 98.36 Very High Very High Very High
Inflammation 1 83.92 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 11 98.36 Very High Very High Very High
INFLAMMATION 1 83.92 Quite High
Appetite Loss 1 60.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Parallel secretion of trypsinogen and PSTI appears to ensure protection against premature activation even under extreme dietary conditions.
Localization (secretion) of PSTI
1) Confidence 0.77 Published 2000 Journal Pancreas Section Abstract Doc Link 10975713 Disease Relevance 0.20 Pain Relevance 0.10
To explore the possibility that PSTI may be secreted at lower levels or contain a mutation in the WBN/Kob rat, we investigated the masses of PSTI-I and -II and asked whether the ratio of PSTI/trypsinogen is decreased in animals with CP.
Localization (secreted) of PSTI associated with chronic pancreatitis
2) Confidence 0.75 Published 2002 Journal Pancreatology Section Abstract Doc Link 12123090 Disease Relevance 0.46 Pain Relevance 0.46
Increased secretion of the pancreatic secretory trypsin inhibitor (PSTI-I, monitor peptide) during development of chronic pancreatitis in the WBN/Kob rat.
Localization (secretion) of PSTI-I associated with chronic pancreatitis
3) Confidence 0.75 Published 2002 Journal Pancreatology Section Title Doc Link 12123090 Disease Relevance 0.35 Pain Relevance 0.42

General Comments

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