INT90607

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.17
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.79
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CPOX) small molecule metabolic process (CPOX) oxidoreductase activity (CPOX)
cytoplasm (CPOX)
CPOX (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 13 99.64 Very High Very High Very High
aspirin 8 99.64 Very High Very High Very High
cINOD 4 91.56 High High
Inflammation 14 62.68 Quite High
Spinal cord 12 56.80 Quite High
COX-2 inhibitor 3 38.08 Quite Low
COX2 2 25.00 Low Low
cOX1 2 25.00 Low Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
allodynia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 4 100.00 Very High Very High Very High
Malignant Neoplastic Disease 1 97.96 Very High Very High Very High
Neuroblastoma 22 97.40 Very High Very High Very High
INFLAMMATION 17 91.08 High High
Erythema 9 5.00 Very Low Very Low Very Low
Burns 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Blister 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After reacting with anti-COX-1 and anti-COX-2 immunoglobulin G, the presence of both immunoreactive COX enzymes was substantiated using an indirect immunoperoxidase method.
Positive_regulation (substantiated) of COX Binding (reacting) of
1) Confidence 0.17 Published 2000 Journal J Ocul Pharmacol Ther Section Abstract Doc Link 10977131 Disease Relevance 0.09 Pain Relevance 0.28
After reacting with anti-COX-1 and anti-COX-2 immunoglobulin G, the presence of both immunoreactive COX enzymes was substantiated using an indirect immunoperoxidase method.
Positive_regulation (substantiated) of COX Binding (reacting) of
2) Confidence 0.17 Published 2000 Journal J Ocul Pharmacol Ther Section Abstract Doc Link 10977131 Disease Relevance 0.09 Pain Relevance 0.28
ATRA increases the activity of the human COX-2 promoter and its effect is inhibited by RAR-pan-antagonist LE540 or MEK-1 inhibitor PD98059
Positive_regulation (by) of COX Binding (activity) of associated with antagonist
3) Confidence 0.10 Published 2007 Journal J Neuroinflammation Section Body Doc Link PMC1769480 Disease Relevance 0.31 Pain Relevance 0.11
It has also been shown that translation of COX-2 mRNA requires the activity of the eIF-5A transcription factor (Parker and Gerner, 2002), the inhibition of which impairs murine melanoma growth (Jasiulionis et al., 2007) and that basal COX-2 expression in melanoma cells is associated with malignant transformation (Ku?
Positive_regulation (requires) of COX Binding (activity) of associated with malignant neoplastic disease and skin cancer
4) Confidence 0.05 Published 2010 Journal Pigment Cell & Melanoma Research Section Body Doc Link PMC2881306 Disease Relevance 0.30 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox