INT90670

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 2000
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 12
Disease Relevance 6.25
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (KRT1) cytoskeleton (KRT1)
Anatomy Link Frequency
smooth muscle 2
brain 2
foot 1
basal layer 1
primitive germ cells 1
KRT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 3 98.24 Very High Very High Very High
Acupuncture 147 95.12 Very High Very High Very High
Neuropeptide 3 87.64 High High
cva 2 84.20 Quite High
Enkephalin 3 79.04 Quite High
headache 1 78.52 Quite High
imagery 21 76.20 Quite High
electroacupuncture 9 75.92 Quite High
Pain 19 75.88 Quite High
Spinal cord 5 75.00 Quite High
Disease Link Frequency Relevance Heat
Cancer 152 99.90 Very High Very High Very High
Persistent Vegetative State 3 99.16 Very High Very High Very High
Stomach Cancer 42 95.84 Very High Very High Very High
Sclerosis 1 94.88 High High
Disease 27 94.08 High High
Necrosis 6 93.56 High High
Malignant Neoplastic Disease 18 93.00 High High
Hemangioma 4 92.64 High High
Endodermal Sinus Tumor 2 92.16 High High
Carcinoma 31 91.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The loose filaments in the former case are composed of “simple-epithelial keratins” like K8/K18 (and K19), while the bundled filaments (tonofilaments) in the latter case (Fig. 1c, d) are built up from keratinocyte-type keratins such as K5/K14 in the basal layer and—with even more pronounced bundling—K1/K10 in the suprabasal layers and K2/K10 in the uppermost ones.
Positive_regulation (bundling) of K1 in basal layer
1) Confidence 0.44 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386534 Disease Relevance 0.19 Pain Relevance 0
Immunohistochemically, both components were positive for cytokeratin and epithelial membrane antigen, but negative for vimentin and desmin.
Positive_regulation (positive) of cytokeratin
2) Confidence 0.39 Published 2000 Journal J Hepatobiliary Pancreat Surg Section Abstract Doc Link 10982621 Disease Relevance 0.95 Pain Relevance 0.10
To summarize, stimulating K1 could arouse the memory, attention, and the self-consciousness-related active area of the brain.
Positive_regulation (stimulating) of K1 in brain
3) Confidence 0.25 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952336 Disease Relevance 0.10 Pain Relevance 0.20
The stimulator was outside the MR scan room and the signal passed through the filter panel to isolate the noise from outdoor of MR scan room to control the laser module stimulating the acupoint K1 on the sole of left foot.
Positive_regulation (stimulating) of K1 in foot
4) Confidence 0.22 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952336 Disease Relevance 0 Pain Relevance 0.04
Therefore, we use LLLT to stimulate K1 (Yongquan) acupoint and observe the related human activations of the human brain.

2.

Positive_regulation (stimulate) of K1 in brain
5) Confidence 0.22 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952336 Disease Relevance 0.18 Pain Relevance 0.45
Immunohistochemically, the tumor cells were positive for glial fibrillary acidic protein (GFAP), epithelial membrane antigen (EMA), vimentin, and negative for cytokeratin, synaptophysin.
Positive_regulation (negative) of cytokeratin associated with cancer
6) Confidence 0.15 Published 2003 Journal Neurol. Res. Section Abstract Doc Link 12870256 Disease Relevance 0.55 Pain Relevance 0.17
Immunohistochemically (IHC), almost all tumors are positive for cytokeratin and epithelial membrane antigen [43].
Positive_regulation (positive) of cytokeratin associated with cancer
7) Confidence 0.04 Published 2006 Journal Diagn Pathol Section Body Doc Link PMC1475889 Disease Relevance 0.83 Pain Relevance 0
Immunohistochemical evaluation was strongly positive for desmin and actin (Figure 3), oestrogen receptor (ER) and progesterone receptor (PR) (Figure 4), but negative for cytokeratin and EMA (Epithelial Membrane Antigen).
Positive_regulation (negative) of cytokeratin
8) Confidence 0.04 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 0.50 Pain Relevance 0
Immunohistochemistry showed that the neoplastic cells were positive for smooth muscle actin and for h-caldesmon and negative for CD34, calponin, FVIII-associated antigen, S100, EMA and cytokeratin AE1 AE3.
Positive_regulation (negative) of cytokeratin AE1 AE3 in smooth muscle
9) Confidence 0.04 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2221972 Disease Relevance 0.74 Pain Relevance 0.04
Immunohistochemical studies showed positive smooth muscle actin and negative cytokeratin, keratin, S100 and desmin.
Positive_regulation (negative) of cytokeratin in smooth muscle
10) Confidence 0.02 Published 2003 Journal Eur. J. Gynaecol. Oncol. Section Abstract Doc Link 14584667 Disease Relevance 0.43 Pain Relevance 0
Immunohistochemical study showed that the primitive germ cells were positive for placental alkaline phosphatase, alpha-fetoprotein, cytokeratin, vimentin, but negative for glial fibrillary acidic protein.
Positive_regulation (positive) of cytokeratin in primitive germ cells
11) Confidence 0.01 Published 2009 Journal Clin Neurol Neurosurg Section Abstract Doc Link 19540038 Disease Relevance 0.93 Pain Relevance 0.08
Immunohistochemical studies revealed the lesional cells to be immunoreactive for CD31 (8/8), CD34 (8/8), Factor VIII (8/8), cytokeratins AE1/AE3 (7/8), cytokeratin 7 (2/8), Cam5.2/cytokeratin 8 (5/8), and cytokeratin 19 (5/8).
Positive_regulation (immunoreactive) of cytokeratin
12) Confidence 0.00 Published 2004 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 15104292 Disease Relevance 0.85 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox