INT90714

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Context Info
Confidence 0.67
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.97
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nr4a2) DNA binding (Nr4a2) response to stress (Nr4a2)
cytoplasm (Nr4a2)
Anatomy Link Frequency
medulla 1
cortex 1
Nr4a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 8 99.06 Very High Very High Very High
qutenza 6 84.04 Quite High
Catecholamine 2 56.80 Quite High
Disease Link Frequency Relevance Heat
Stress 14 99.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Surprisingly, only NGFI-B and Nurr1 were induced in the glucocorticoid secreting regions of zonae reticularis and fasciculata of the cortex, starting 15 min after the stress.
Positive_regulation (induced) of Nurr1 in cortex associated with stress
1) Confidence 0.67 Published 2000 Journal Brain Res. Section Abstract Doc Link 10986333 Disease Relevance 0.49 Pain Relevance 0.37
NGFI-A was induced in medulla within 15 min after stress, NGFI-B, egr-3 and Nurr1 were induced by 30 min, whereas NGFI-C was induced by 2 h.
Positive_regulation (induced) of Nurr1 in medulla associated with stress and medulla
2) Confidence 0.45 Published 2000 Journal Brain Res. Section Abstract Doc Link 10986333 Disease Relevance 0.48 Pain Relevance 0.34

General Comments

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