INT90748

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Context Info
Confidence 0.69
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.48
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gpd1) mitochondrion (Gpd1) carbohydrate metabolic process (Gpd1)
cytoplasm (Gpd1)
Anatomy Link Frequency
spinal cord 2
Gpd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 4 97.84 Very High Very High Very High
Morphine 4 92.52 High High
Analgesic 4 92.08 High High
narcan 2 91.40 High High
antagonist 2 91.04 High High
opioid receptor 2 90.60 High High
aspirin 2 86.40 High High
Pain 2 77.76 Quite High
analgesia 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Convulsion 4 90.68 High High
INFLAMMATION 2 88.24 High High
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nevertheless, in all cases, induction of the GPDH gene requires adrenal steroids and new protein synthesis, as the induction was blocked in adrenalectomized rats and by cycloheximide treatment, respectively.
Positive_regulation (requires) of Positive_regulation (induction) of GPDH gene
1) Confidence 0.69 Published 2000 Journal J. Neurochem. Section Abstract Doc Link 10987821 Disease Relevance 0.23 Pain Relevance 0.75
Northern blot and in situ hybridization analysis confirmed the differential display results; they also showed, in a separate model of neuronal activation, that after thermal noxious stimulation of the hind-paws, a similar increase in GPDH mRNA occurs in the areas of somatotopic projection in the lumbar spinal cord.
Positive_regulation (occurs) of Positive_regulation (increase) of GPDH in spinal cord associated with spinal cord
2) Confidence 0.50 Published 2000 Journal J. Neurochem. Section Abstract Doc Link 10987821 Disease Relevance 0.25 Pain Relevance 0.58

General Comments

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