INT90807

Context Info Confidence 0.00 First Reported 2000 Last Reported 2000 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.39 Pain Relevance 0.39

plasma membrane (EGF, Oprd1) signal transduction (EGF) extracellular space (EGF) extracellular region (EGF) cytoplasm (Oprd1) signal transducer activity (Oprd1)

EGF (Homo sapiens) Oprd1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat opioid receptor 1 100.00 MU agonist 1 99.62 Opioid 3 95.44 Analgesic 1 25.00

Disease Link Frequency Relevance Heat Bordatella Infection 5 93.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Chronic treatment with micro or kappa opioid agonists (>/=2 h) inhibits EGF-induced ERK activation in opioid receptor overexpressing COS-7 cells.

EGF Positive_regulation (activation) of opioid receptor associated with mu agonist and opioid receptor

1) Confidence 0.00 Published 2000 Journal Cell. Signal. Section Abstract Doc Link 10989284 Disease Relevance 0.39 Pain Relevance 0.39

General Comments

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