INT9081

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Context Info
Confidence 0.42
First Reported 1992
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 7.13
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
eosinophil 2
IGHE (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 8 100.00 Very High Very High Very High
Inflammation 44 98.22 Very High Very High Very High
Pain 3 93.88 High High
Angina 3 92.80 High High
COX2 3 73.60 Quite High
Inflammatory response 7 73.36 Quite High
pruritus 1 64.36 Quite High
cytokine 22 22.24 Low Low
alcohol 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorders Of Creatine Metabolism 5 100.00 Very High Very High Very High
Eczema 34 99.70 Very High Very High Very High
Infection 21 99.56 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 9 99.36 Very High Very High Very High
Eosinophilia 7 99.36 Very High Very High Very High
Esophageal Disease 36 98.74 Very High Very High Very High
Cytomegalovirus Infection 1 98.48 Very High Very High Very High
INFLAMMATION 49 98.22 Very High Very High Very High
Myocardial Infarction 3 98.00 Very High Very High Very High
Viral Infection 4 96.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Laboratory examinations revealed eosinophilia (WBC 3940/mm3, eosinophil 9%), elevated ESR, and an elevated serum total IgE level (5517 IU/ml).
Positive_regulation (elevated) of Positive_regulation (elevated) of IgE in eosinophil associated with eosinophilia
1) Confidence 0.42 Published 1992 Journal Nihon Kyobu Shikkan Gakkai Zasshi Section Abstract Doc Link 1387180 Disease Relevance 1.29 Pain Relevance 0.09
HIV infection is a well-recognized cause for elevated IgE levels [46-48].
Positive_regulation (cause) of Positive_regulation (elevated) of IgE associated with acquired immune deficiency syndrome or hiv infection and infection
2) Confidence 0.41 Published 2010 Journal Clin Mol Allergy Section Body Doc Link PMC2837605 Disease Relevance 2.37 Pain Relevance 0
For anti-inflammatory molecules and esophagitis risk, Khurana Hershey et al. demonstrated that IL4R:rs1801275 resulted in enhanced IL4 signaling and the induction of high levels of the IgE receptor CD23 [25].
Positive_regulation (resulted) of Positive_regulation (induction) of IgE associated with esophageal disease and inflammation
3) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2928273 Disease Relevance 0.79 Pain Relevance 0.21
Ninety percent of patients with AD have markedly elevated total IgE levels and high levels of specific IgE.
Positive_regulation (elevated) of Positive_regulation (levels) of IgE associated with eczema
4) Confidence 0.14 Published 2006 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2876187 Disease Relevance 1.36 Pain Relevance 0.09
Compared with normal subjects, increased IgE but unchanged MMP-9, CPK, LDH were found in SAP group and UAP group, whereas IgE, MMP-9, CPK and LDH levels were all significantly increased in AMI group.
Positive_regulation (increased) of Neg (unchanged) Positive_regulation (increased) of IgE associated with disorders of creatine metabolism and metalloproteinase
5) Confidence 0.11 Published 2007 Journal Chin J Physiol Section Abstract Doc Link 18442010 Disease Relevance 1.32 Pain Relevance 0.61

General Comments

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