INT90940

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Context Info
Confidence 0.35
First Reported 2000
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.92
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Eng) cell motility (Eng) cell adhesion (Eng)
nucleus (Eng) cytoplasm (Eng)
Anatomy Link Frequency
vasculature 1
Eng (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 1 84.52 Quite High
imagery 24 82.08 Quite High
Inflammation 3 5.12 Low Low
Kinase C 9 5.00 Very Low Very Low Very Low
positron emission tomography 7 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 3 99.04 Very High Very High Very High
Cancer 97 98.20 Very High Very High Very High
Angina 1 84.52 Quite High
Disease 41 81.48 Quite High
Immunotherapy Of Cancer 2 80.32 Quite High
Breast Cancer 1 80.04 Quite High
Glioma 1 79.28 Quite High
Hemangiosarcoma 1 78.96 Quite High
Coronary Artery Disease 1 75.00 Quite High
Diabetic Retinopathy 2 66.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
1 signaling via endoglin or ALK-1 on ECs is associated with vessel destabilization, EC proliferation and migration, by limiting TGF-?
endoglin Binding (signaling) of
1) Confidence 0.35 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2659748 Disease Relevance 0.23 Pain Relevance 0
1 signaling via endoglin or ALK-1 on ECs is associated with vessel destabilization, EC proliferation and migration, by limiting TGF-?
endoglin Binding (associated) of
2) Confidence 0.35 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2659748 Disease Relevance 0.23 Pain Relevance 0
In contrast, patients with TVD had more CD105/TGFbeta1 complex in their sera than the other two groups, suggesting that this may be the reason why TVD patients had low levels of receptor and ligand.
CD105 Binding (complex) of
3) Confidence 0.19 Published 2000 Journal Atherosclerosis Section Abstract Doc Link 10996361 Disease Relevance 0.29 Pain Relevance 0.08
We found that targeting to VEGFR2, endoglin, or the VEGF:VEGFR complex was specific for tumor vasculature as there was no signal enhancement in nontumor tumor tissue.
endoglin Binding (targeting) of in vasculature associated with cancer
4) Confidence 0.10 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2902148 Disease Relevance 1.17 Pain Relevance 0.04
-secretase activity: CD147 is a transmembrane glycoprotein and interacts with all four essential ?
transmembrane glycoprotein Binding (interacts) of
5) Confidence 0.03 Published 2011 Journal Mol Brain Section Body Doc Link PMC3022812 Disease Relevance 0 Pain Relevance 0

General Comments

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