INT91087

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Context Info
Confidence 0.29
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Prkcg) response to stress (Prkcg) cytoplasm (Prkcg)
cell-cell signaling (SST) cytosol (Prkcg) extracellular space (SST)
Anatomy Link Frequency
smooth muscle cells 2
SST (Homo sapiens)
Prkcg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 7 100.00 Very High Very High Very High
Somatostatin 2 100.00 Very High Very High Very High
Cholecystokinin 1 100.00 Very High Very High Very High
opioid receptor 1 98.68 Very High Very High Very High
adenocard 1 96.00 Very High Very High Very High
agonist 1 54.56 Quite High
Enkephalin 1 37.04 Quite Low
Disease Link Frequency Relevance Heat
Natriuresis 1 53.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of PKC by pretreatment of intestinal smooth muscle cells with phorbol 12-myristate 13-acetate, cholecystokinin octapeptide, or the phosphatase 1 and phosphatase 2A inhibitor, calyculin A, selectively phosphorylated Galpha(i-1) and Galpha(i-2), but not Galpha(i-3) or Galpha(o), and blocked inhibition of adenylyl cyclase mediated by somatostatin receptors coupled to G(i-1) and opioid receptors coupled to G(i-2), but not by muscarinic M(2) and adenosine A(1) receptors coupled to G(i-3).
somatostatin Positive_regulation (mediated) of Positive_regulation (Activation) of PKC in smooth muscle cells associated with adenocard, kinase c, somatostatin, opioid receptor and cholecystokinin
1) Confidence 0.29 Published 2000 Journal Am. J. Physiol., Cell Physiol. Section Abstract Doc Link 11003572 Disease Relevance 0.05 Pain Relevance 0.43

General Comments

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