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Context Info
Confidence 0.78
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.13
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CAT) small molecule metabolic process (CAT) aging (CAT)
Golgi apparatus (CAT) endoplasmic reticulum (CAT) peroxisome (CAT)
Anatomy Link Frequency
gastric juices 1
skin 1
bile 1
SH3 1
CAT (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 4 100.00 Very High Very High Very High
Pain 2 97.92 Very High Very High Very High
Inflammation 34 96.76 Very High Very High Very High
Osteoarthritis 36 92.40 High High
spinal inflammation 86 90.96 High High
rheumatoid arthritis 39 79.32 Quite High
psoriasis 63 75.60 Quite High
Glutamate 5 65.92 Quite High
Enkephalin 1 25.84 Quite Low
cINOD 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 16 100.00 Very High Very High Very High
Pain 2 97.92 Very High Very High Very High
INFLAMMATION 39 96.76 Very High Very High Very High
Dysphagia 1 96.60 Very High Very High Very High
Disorder Of Lipid Metabolism 33 95.76 Very High Very High Very High
Esophageal Cancer 1 94.96 High High
Ulcers 4 93.60 High High
Frailty 40 92.40 High High
Low Back Pain 85 90.96 High High
Cancer 12 89.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CAT is used to release radioactive elemental iodine by oxidation of its salts.
Localization (release) of CAT
1) Confidence 0.78 Published 2001 Journal Anal. Biochem. Section Abstract Doc Link 11141301 Disease Relevance 0 Pain Relevance 0
It was shown that water extract of HP can activate neutrophils and enhance the secretion of MPO.39 CAT is a ubiquitous, well-studied enzyme that catalyses the decomposition of hydrogen peroxide (H2O2) into water and oxygen to protect cells from the damaging effects of H2O2.24 HP has been shown to produce CAT, but the reported amount of this enzyme secreted would not be sufficient to scavenge extra cellular oxidants.40 Almost all the previous studies on the association of with HP in adult population were performed in gastric mucosa.12,21,23 Some previous studies have reported that no CAT activity was found in most gastric juices, probably because of their low pH levels, and in some antral tissue specimens.41,42 Akcan, et al.2 reported no unchanged of MPO and SOD activity in gastric mucosa of childhood period with HP (+) and (-) subjects, and Bulbuloglu, et al.42 also reported no unchanged of CAT activity in antral mucosal between HP (+) and (-) subjects.
Localization (secretion) of CAT in gastric juices associated with urological neuroanatomy
2) Confidence 0.78 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2768243 Disease Relevance 0.82 Pain Relevance 0.09
Endoscopy, barium swallow and a CAT scan all pointed to extramucosal localization.
Localization (localization) of CAT
3) Confidence 0.73 Published 2000 Journal Dis. Esophagus Section Abstract Doc Link 11005337 Disease Relevance 1.24 Pain Relevance 0.20
The skin antioxidant system consists of a network of both enzymatic (glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD), and paraoxonase (PON1)) and nonenzymatic antioxidants.
Localization (network) of CAT in skin
4) Confidence 0.73 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2914266 Disease Relevance 0.68 Pain Relevance 0.14
These proteins were identified as Ig gamma-1 chain C region, dynein heavy chain, fibrinogen gamma chain precursor, catalase, SH3 and multiple ankyrin repeat domains protein 2, haptoglobin precursor, DNA-dependent protein kinase catalytic subunit, apolipoprotein A-I precursor, serotransferrin precursor, microtubule-actin crosslinking factor 1 isoform 4, and intersectin 1.
Localization (multiple) of catalase in SH3 associated with disorder of lipid metabolism
5) Confidence 0.04 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC3012668 Disease Relevance 1.18 Pain Relevance 0.67
Genes encoding urease, bile salts efflux pump, adhesin, catalase, superoxide dismutase, and other putative virulence factors—such as hemolysins, RTX toxins, patatin-like proteins, phospholipase A1, and collagenases—are present.
Localization (urease) of catalase in bile associated with bile
6) Confidence 0.01 Published 2009 Journal PLoS Genetics Section Abstract Doc Link PMC2652115 Disease Relevance 0.22 Pain Relevance 0.08

General Comments

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