INT91160

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Context Info
Confidence 0.26
First Reported 2000
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 3.12
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (DMBT1) proteinaceous extracellular matrix (DMBT1) intracellular (DMBT1)
cytoplasm (DMBT1)
Anatomy Link Frequency
lung 4
saliva 2
DMBT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
peptic ulcer disease 8 97.80 Very High Very High Very High
dorsal root ganglion 1 56.96 Quite High
Spinal cord 2 49.36 Quite Low
nociceptor 1 25.00 Low Low
Inflammation 2 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gastritis 25 100.00 Very High Very High Very High
Apoptosis 1 99.68 Very High Very High Very High
Ulcers 9 97.80 Very High Very High Very High
Dental Caries 8 97.80 Very High Very High Very High
Disease 23 97.28 Very High Very High Very High
Sepsis 7 96.84 Very High Very High Very High
Nociception 1 86.64 High High
Ganglion Cysts 1 56.00 Quite High
Cancer 22 50.00 Quite Low
Infection 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunoblotting with antibodies that specifically recognized either lung gp-340 or the agglutinin confirmed that the salivary agglutinin was gp-340.
agglutinin Binding (recognized) of in lung
1) Confidence 0.26 Published 2000 Journal J. Biol. Chem. Section Abstract Doc Link 11007786 Disease Relevance 0.51 Pain Relevance 0.07
Salivary agglutinin is a high molecular mass component of human saliva that binds Streptococcus mutans, an oral bacterium implicated in dental caries.
agglutinin Binding (binds) of in saliva associated with dental caries
2) Confidence 0.26 Published 2000 Journal J. Biol. Chem. Section Abstract Doc Link 11007786 Disease Relevance 0.17 Pain Relevance 0
The salivary agglutinin also interacted with Helicobacter pylori, implicated in gastritis and peptic ulcer disease, Streptococcus agalactiae, implicated in neonatal meningitis, and several oral commensal streptococci.
agglutinin Binding (interacted) of associated with peptic ulcer disease, disease, gastritis and sepsis
3) Confidence 0.26 Published 2000 Journal J. Biol. Chem. Section Abstract Doc Link 11007786 Disease Relevance 0.62 Pain Relevance 0.10
Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340.
agglutinin Binding (binds) of in lung associated with gastritis
4) Confidence 0.26 Published 2000 Journal J. Biol. Chem. Section Title Doc Link 11007786 Disease Relevance 0.19 Pain Relevance 0
These results identify the salivary agglutinin as gp-340 and suggest it binds bacteria that are important determinants of either the oral ecology or systemic diseases.
agglutinin Binding (binds) of associated with disease
5) Confidence 0.20 Published 2000 Journal J. Biol. Chem. Section Abstract Doc Link 11007786 Disease Relevance 0.64 Pain Relevance 0.09
Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340.
gp-340 Binding (binds) of in lung associated with gastritis
6) Confidence 0.19 Published 2000 Journal J. Biol. Chem. Section Title Doc Link 11007786 Disease Relevance 0.24 Pain Relevance 0
Immunoblotting with antibodies that specifically recognized either lung gp-340 or the agglutinin confirmed that the salivary agglutinin was gp-340.
gp-340 Binding (recognized) of in lung
7) Confidence 0.17 Published 2000 Journal J. Biol. Chem. Section Abstract Doc Link 11007786 Disease Relevance 0.50 Pain Relevance 0.07
Possible associated proteins of salivary mRNA may be apoptotic bodies of desquamated mucosal cells [22, 34] and several saliva proteins like mucines [34].
salivary mRNA Binding (associated) of in saliva associated with apoptosis
8) Confidence 0.02 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674305 Disease Relevance 0.10 Pain Relevance 0
Previous studies have shown that the plant lectin Ulex europaeus agglutinin-I (UEA) binds to a population of small to medium diameter primary sensory neurones in rabbits and humans.
agglutinin-I Binding (binds) of
9) Confidence 0.01 Published 2002 Journal Histochem. J. Section Abstract Doc Link 12365803 Disease Relevance 0.14 Pain Relevance 0.03

General Comments

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