INT91210

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Context Info
Confidence 0.41
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.76
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Mrgpre) plasma membrane (Mrgpre) molecular_function (Mrgpre)
cellular_component (Mrgpre) biological_process (Mrgpre) signal transducer activity (Mrgpre)
Mrgpre (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 23 100.00 Very High Very High Very High
Bile 3 75.00 Quite High
Neuropathic pain 3 66.72 Quite High
allodynia 17 5.00 Very Low Very Low Very Low
Eae 11 5.00 Very Low Very Low Very Low
Sciatic nerve 11 5.00 Very Low Very Low Very Low
Spinal cord 9 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 25 100.00 Very High Very High Very High
Prostate Cancer 56 99.02 Very High Very High Very High
Recurrence 15 96.64 Very High Very High Very High
Nociception 4 96.52 Very High Very High Very High
Pancreatic Cancer 3 94.92 High High
Cancer 48 87.52 High High
Bile Duct Neoplasms 2 69.40 Quite High
Sarcoma 35 68.96 Quite High
Neuropathic Pain 22 66.72 Quite High
Gallstones 1 61.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EBRT is indicated at best for local pain control and is limited by the high radiation sensitivity of the adjacent organs.
Negative_regulation (limited) of EBRT associated with pain
1) Confidence 0.41 Published 2000 Journal Praxis Section Abstract Doc Link 11014129 Disease Relevance 0.77 Pain Relevance 0.21
We generated mutant mice lacking MrgE and examined the effects of deletion of this gene in three pain behavioural models.
Negative_regulation (lacking) of MrgE associated with pain
2) Confidence 0.38 Published 2008 Journal Mol Pain Section Abstract Doc Link PMC2242784 Disease Relevance 0.53 Pain Relevance 0.32
brachytherapy, two patients declined EBRT, and one patient died of
Negative_regulation (declined) of EBRT
3) Confidence 0.19 Published 2006 Journal Sarcoma Section Body Doc Link PMC1557794 Disease Relevance 0.63 Pain Relevance 0
The issue of RT–HT in low-risk PC patients was also indirectly addressed by a retrospective analysis conducted by Ciezki et al.28 The study included 1,668 patients with low- and intermediate-risk PC treated at The Cleveland Clinic Foundation with EBRT, RP, or prostate brachytherapy with or without androgen deprivation during 1996–2001.
Negative_regulation (deprivation) of EBRT associated with prostate cancer
4) Confidence 0.12 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004567 Disease Relevance 0.83 Pain Relevance 0

General Comments

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