INT91220

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Context Info
Confidence 0.02
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ptgs1) nuclear envelope (Ptgs1) oxidoreductase activity (Ptgs1)
Golgi apparatus (Ptgs1) endoplasmic reticulum (Ptgs1) plasma membrane (Ptgs1)
Ptgs1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 1 99.84 Very High Very High Very High
cINOD 4 99.34 Very High Very High Very High
COX-2 inhibitor 1 89.20 High High
COX2 1 25.00 Low Low
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 99.84 Very High Very High Very High
Cancer 5 99.16 Very High Very High Very High
Colon Cancer 1 98.16 Very High Very High Very High
Familial Adenomatous Polyposis 3 96.48 Very High Very High Very High
Adenoma 5 85.76 High High
Ulcers 1 25.00 Low Low
Toxicity 1 25.00 Low Low
Syndrome 1 25.00 Low Low
Hemorrhage 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NSAIDs nonselectively inhibit both the constitutive cyclooxygenase (COX) 1 associated with side effects and the desired therapeutic target COX-2, which is induced in inflammation and neoplasia.
Positive_regulation (induced) of constitutive cyclooxygenase Binding (associated) of associated with inflammation, cancer and cinod
1) Confidence 0.02 Published 2000 Journal Cancer Res. Section Abstract Doc Link 11016626 Disease Relevance 0.76 Pain Relevance 0.47

General Comments

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