INT9123

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Context Info
Confidence 0.61
First Reported 1987
Last Reported 1992
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.50
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Hal) lyase activity (Hal) biosynthetic process (Hal)
cytoplasm (Hal)
Anatomy Link Frequency
blood 2
liver 1
Hal (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 1 100.00 Very High Very High Very High
Serotonin 1 100.00 Very High Very High Very High
antagonist 1 100.00 Very High Very High Very High
narcan 8 98.54 Very High Very High Very High
Enkephalin 2 90.48 High High
Neuropeptide 1 76.40 Quite High
Disease Link Frequency Relevance Heat
Gallstones 4 99.72 Very High Very High Very High
Stress 2 99.04 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A combined injection of dalargin and naloxone promoted high release of histidase and urokaninase in blood and did not change histidase activity in the liver in all cases.
Neg (not) Regulation (change) of histidase in liver associated with narcan
1) Confidence 0.61 Published 1992 Journal Biull Eksp Biol Med Section Abstract Doc Link 1391860 Disease Relevance 0.13 Pain Relevance 0.36
Experiments were conducted on 182 rats with acute cholestasis to study the effect of intra-abdominal dalargin injection (10 mcg/kg) with the serotonin antagonist ketanserine (150 mg/kg) on xanthine oxidase (XO) activity and level of lipid peroxidation in the hepatic tissue and on the activity of the hepatospecific enzymes histidase and urokaninase in hepatic tissue and blood serum 1, 3, and 5 hours after the injection.
Regulation (effect) of histidase in blood associated with antagonist, gallstones and serotonin
2) Confidence 0.25 Published 1990 Journal Patol Fiziol Eksp Ter Section Abstract Doc Link 2080086 Disease Relevance 0.17 Pain Relevance 0.10
Influence of the Hal locus and standardized stress on antibody response and in vitro reactivity of peripheral blood lymphocytes in pigs.
Regulation (Influence) of Hal in blood associated with stress and anesthesia
3) Confidence 0.05 Published 1987 Journal Vet. Immunol. Immunopathol. Section Title Doc Link 3564363 Disease Relevance 0.19 Pain Relevance 0.10

General Comments

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