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Context Info
Confidence 0.43
First Reported 2000
Last Reported 2000
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Prkaca, Oprm1) mitochondrion (Prkaca) Golgi apparatus (Prkaca)
protein complex (Prkaca) signal transducer activity (Oprm1) cytoplasm (Prkaca)
Prkaca (Mus musculus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 3 100.00 Very High Very High Very High
tolerance 10 99.80 Very High Very High Very High
Opioid 2 98.00 Very High Very High Very High
Intracerebroventricular 1 96.56 Very High Very High Very High
intrathecal 1 93.60 High High
MU agonist 2 75.00 Quite High
Morphine 6 72.24 Quite High
Immobilon 10 60.64 Quite High
analgesia 1 44.16 Quite Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we examined the role of cAMP-PKA on mu-opioid receptor downregulation and tolerance in mice.
cAMP-PKA Spec (examined) Regulation (role) of Spec (examined) Negative_regulation (downregulation) of mu-opioid receptor associated with tolerance and opioid receptor
1) Confidence 0.43 Published 2000 Journal Synapse Section Abstract Doc Link 11020235 Disease Relevance 0 Pain Relevance 0.76

General Comments

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