INT91274

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Context Info
Confidence 0.42
First Reported 2000
Last Reported 2007
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 1.12
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il2) extracellular region (Il2)
Anatomy Link Frequency
locus coeruleus 2
prefrontal 2
Il2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 2 100.00 Very High Very High Very High
Pain 2 100.00 Very High Very High Very High
withdrawal 1 100.00 Very High Very High Very High
Locus ceruleus 6 99.60 Very High Very High Very High
cerebral cortex 9 97.80 Very High Very High Very High
Intracerebroventricular 1 88.96 High High
Dorsal horn 1 80.32 Quite High
Neurotransmitter 1 77.36 Quite High
amygdala 2 74.24 Quite High
opioid receptor 1 67.80 Quite High
Disease Link Frequency Relevance Heat
Nociception 4 100.00 Very High Very High Very High
Anxiety Disorder 85 98.60 Very High Very High Very High
Cancer 1 84.56 Quite High
Necrosis 1 84.08 Quite High
Targeted Disruption 2 81.08 Quite High
Hypertrophy 1 38.88 Quite Low
Syndrome 3 21.32 Low Low
Endometriosis (extended) 10 20.04 Low Low
Depression 6 11.76 Low Low
Hyperlipidemia 2 5.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, a decrease in open arm time and an increase in IL-2 level in the prefrontal cortex of LA OVX rats were seen after treatment with dioscorea at 250 mg/kg/day.
Negative_regulation (decrease) of Positive_regulation (increase) of IL-2 in prefrontal associated with anxiety disorder
1) Confidence 0.42 Published 2007 Journal Ann Gen Psychiatry Section Body Doc Link PMC1971263 Disease Relevance 0.84 Pain Relevance 0.17
Inhibition of nociceptive withdrawal reflex by microinjection of interleukin 2 into rat locus coeruleus.
Negative_regulation (Inhibition) of Positive_regulation (microinjection) of interleukin 2 in locus coeruleus associated with nociception, locus ceruleus, narcan and withdrawal
2) Confidence 0.27 Published 2000 Journal Neuropeptides Section Title Doc Link 11021983 Disease Relevance 0.28 Pain Relevance 0.57

General Comments

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