INT91278

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Context Info
Confidence 0.31
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.73
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgb3) plasma membrane (Itgb3)
Anatomy Link Frequency
platelet 1
endometrium 1
Itgb3 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 6 99.74 Very High Very High Very High
Angina 1 95.88 Very High Very High Very High
aspirin 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
endometriosis 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 5 99.74 Very High Very High Very High
Cv Unclassified Under Development 3 99.68 Very High Very High Very High
Myocardial Infarction 6 99.32 Very High Very High Very High
Acute Coronary Syndrome 53 92.12 High High
Rupture 2 88.40 High High
Atherosclerotic Plaque 2 87.80 High High
Thrombosis 4 86.76 High High
Coronary Artery Disease 15 74.60 Quite High
Acute Myeloid Leukemia 8 66.08 Quite High
Myeloid Leukemia 2 52.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Itgb3 mRNA levels significantly increased after up-regulation of Meis1 expression with MEIS1 cDNA.
Positive_regulation (increased) of Itgb3
1) Confidence 0.31 Published 2008 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2387222 Disease Relevance 0.12 Pain Relevance 0
In contrast, Itgb3 protein levels were increased in endometrium transfected with the pcDNA4/MEIS1 expression construct compared with the control (see legend to Fig. 7).
Positive_regulation (increased) of Itgb3 in endometrium
2) Confidence 0.31 Published 2008 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2387222 Disease Relevance 0 Pain Relevance 0
Clinical symptoms of acute coronary insufficiency correlate with GP-IIIa genotype of integrin beta-subunit.
Positive_regulation (genotype) of GP-IIIa associated with cv unclassified under development
3) Confidence 0.03 Published 2000 Journal Bull. Exp. Biol. Med. Section Title Doc Link 11022255 Disease Relevance 0.39 Pain Relevance 0.10
A recent study has shown patients with acute myocardial infarction (MI) and unstable angina have higher levels of platelet CD154 and P-selectin as compared to those with stable angina or healthy volunteers [23].
Positive_regulation (levels) of platelet CD154 in platelet associated with cva and myocardial infarction
4) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954807 Disease Relevance 1.22 Pain Relevance 0.10

General Comments

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