INT91324

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.73
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 2.08
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL4) extracellular space (CCL4) extracellular region (CCL4)
cell adhesion (CCL4) cell-cell signaling (CCL4)
Anatomy Link Frequency
macrophages 1
sciatic nerves 1
B-cells 1
DCs 1
CCL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 17 100.00 Very High Very High Very High
Inflammation 101 99.54 Very High Very High Very High
Sciatic nerve 1 99.48 Very High Very High Very High
Neuritis 2 96.60 Very High Very High Very High
Peripheral nervous system 3 84.76 Quite High
tolerance 39 66.64 Quite High
Nerve growth factor 3 62.60 Quite High
cytokine 112 50.00 Quite Low
Pain 7 50.00 Quite Low
Crohn's disease 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 95 99.54 Very High Very High Very High
Experimental Autoimmune Neuritis 2 97.56 Very High Very High Very High
Demyelinating Disease 5 83.24 Quite High
Immunization 1 77.92 Quite High
Disease 68 74.80 Quite High
Autoimmune Disease 36 73.48 Quite High
Apoptosis 9 72.40 Quite High
Necrosis 6 61.52 Quite High
Cancer 99 61.16 Quite High
Pain 6 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study we report the expression pattern of the chemokines interferon-gamma-inducible protein (IP)-10, monocyte chemoattractant protein (MCP)-1, macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and regulated upon activation normal T cell expressed and secreted (RANTES) in sciatic nerves from animals with myelin-induced experimental autoimmune neuritis, using a semiquantitative reverse transcriptase-PCR dot-blot hybridization assay.
Localization (secreted) of MIP-1beta in sciatic nerves associated with chemokine, inflammation, experimental autoimmune neuritis, sciatic nerve and neuritis
1) Confidence 0.73 Published 2000 Journal J. Neuroimmunol. Section Abstract Doc Link 11024541 Disease Relevance 0.74 Pain Relevance 0.60
The presence of IFN-gamma, IL-6, MCP-1, or MIP-1beta performed as well as magnetic resonance imaging in the prediction of intraoperative findings.
Localization (presence) of MIP-1beta
2) Confidence 0.73 Published 2009 Journal J Bone Joint Surg Am Section Body Doc Link 19797564 Disease Relevance 0 Pain Relevance 0
In fact activated professional APCs (DCs, B-cells, and macrophages) can attract Tregs, through the secretion of common chemokines, such as CCL4, which is the most potent chemoattractan of Tregs [49].
Localization (secretion) of CCL4 in DCs associated with chemokine
3) Confidence 0.42 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2821644 Disease Relevance 0.45 Pain Relevance 0.11
In fact activated professional APCs (DCs, B-cells, and macrophages) can attract Tregs, through the secretion of common chemokines, such as CCL4, which is the most potent chemoattractan of Tregs [49].
Localization (secretion) of CCL4 in macrophages associated with chemokine
4) Confidence 0.14 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2821644 Disease Relevance 0.45 Pain Relevance 0.11
In fact activated professional APCs (DCs, B-cells, and macrophages) can attract Tregs, through the secretion of common chemokines, such as CCL4, which is the most potent chemoattractan of Tregs [49].
Localization (secretion) of CCL4 in B-cells associated with chemokine
5) Confidence 0.14 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2821644 Disease Relevance 0.45 Pain Relevance 0.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox