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Context Info
Confidence 0.78
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.97
Pain Relevance 1.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (MIP) transmembrane transport (MIP)
Anatomy Link Frequency
sciatic nerves 1
microglia 1
MIP (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 39 100.00 Very High Very High Very High
Inflammation 87 99.80 Very High Very High Very High
cytokine 77 99.52 Very High Very High Very High
Sciatic nerve 1 99.48 Very High Very High Very High
Neuritis 3 96.60 Very High Very High Very High
Inflammatory mediators 7 94.28 High High
rheumatoid arthritis 98 93.52 High High
Inflammatory response 8 87.84 High High
Arthritis 89 86.48 High High
Peripheral nervous system 3 85.28 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 105 99.80 Very High Very High Very High
Experimental Autoimmune Neuritis 2 97.56 Very High Very High Very High
Rheumatoid Arthritis 99 93.52 High High
Apoptosis 84 93.44 High High
Lyme Disease 13 91.24 High High
Neuroblastoma 5 90.48 High High
Lyme Neuroborreliosis 5 88.64 High High
Arthritis 91 86.48 High High
Demyelinating Disease 2 83.76 Quite High
Immunization 6 77.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, RASFs release MIP-3?
Localization (release) of MIP
1) Confidence 0.78 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246247 Disease Relevance 0.23 Pain Relevance 0.23
In this model, release of chemokines (IL-8, MCP-1, IP-10 and MIP-1?)
Localization (release) of MIP associated with chemokine
2) Confidence 0.78 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246249 Disease Relevance 0.76 Pain Relevance 0.59
In experiments where B. burgdorferi was co-cultured in vitro with primary microglia, we observed robust expression and release of IL-6 and IL-8, CCL2 (MCP-1), CCL3 (MIP-1?)
Localization (release) of MIP in microglia
3) Confidence 0.78 Published 2009 Journal PLoS Pathogens Section Abstract Doc Link PMC2771360 Disease Relevance 1.08 Pain Relevance 0.16
In the present study we report the expression pattern of the chemokines interferon-gamma-inducible protein (IP)-10, monocyte chemoattractant protein (MCP)-1, macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and regulated upon activation normal T cell expressed and secreted (RANTES) in sciatic nerves from animals with myelin-induced experimental autoimmune neuritis, using a semiquantitative reverse transcriptase-PCR dot-blot hybridization assay.
Localization (secreted) of MIP in sciatic nerves associated with chemokine, inflammation, experimental autoimmune neuritis, sciatic nerve and neuritis
4) Confidence 0.73 Published 2000 Journal J. Neuroimmunol. Section Abstract Doc Link 11024541 Disease Relevance 0.75 Pain Relevance 0.60
Secretion of MIP-1?
Localization (Secretion) of MIP
5) Confidence 0.73 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC1913569 Disease Relevance 0.15 Pain Relevance 0.20

General Comments

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