INT91339

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Context Info
Confidence 0.28
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 0.34
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Lep, Cck) extracellular region (Lep, Cck) signal transduction (Lep)
intracellular (Lep) lipid metabolic process (Lep)
Anatomy Link Frequency
PVN 1
Lep (Mus musculus)
Cck (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 5 89.04 High High
qutenza 5 86.16 High High
Disease Link Frequency Relevance Heat
Body Weight 5 93.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The dampening of CCK or leptin inhibitory action on ingestive behavior when either factor is not present or their receptors are non functional supports the notion that such leptin-CCK interaction may have a physiological relevance.
leptin Binding (interaction) of CCK
1) Confidence 0.28 Published 2000 Journal Regul. Pept. Section Abstract Doc Link 11024569 Disease Relevance 0.06 Pain Relevance 0.11
The dampening of CCK or leptin inhibitory action on ingestive behavior when either factor is not present or their receptors are non functional supports the notion that such leptin-CCK interaction may have a physiological relevance.
leptin Binding (interaction) of CCK
2) Confidence 0.27 Published 2000 Journal Regul. Pept. Section Abstract Doc Link 11024569 Disease Relevance 0.06 Pain Relevance 0.10
The dampening of CCK or leptin inhibitory action on ingestive behavior when either factor is not present or their receptors are non functional supports the notion that such leptin-CCK interaction may have a physiological relevance.
leptin Binding (interaction) of CCK
3) Confidence 0.27 Published 2000 Journal Regul. Pept. Section Abstract Doc Link 11024569 Disease Relevance 0.06 Pain Relevance 0.10
Synergistic interaction between CCK and leptin to regulate food intake.
leptin Binding (interaction) of CCK
4) Confidence 0.27 Published 2000 Journal Regul. Pept. Section Title Doc Link 11024569 Disease Relevance 0.09 Pain Relevance 0.12
CCK co-injected with leptin potentiated Fos expression selectively in the area postrema, NTS and paraventricular nucleus of the hypothalamus (PVN), which points to the PVN as part of the afferent and efferent limbs of the circuitry involved in the synergistic interaction between leptin and CCK.
leptin Binding (interaction) of CCK in PVN
5) Confidence 0.27 Published 2000 Journal Regul. Pept. Section Abstract Doc Link 11024569 Disease Relevance 0.07 Pain Relevance 0.12

General Comments

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