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Context Info
Confidence 0.36
First Reported 2000
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.78
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crh, Gnrh1) extracellular region (Crh, Gnrh1) molecular_function (Gnrh1)
response to stress (Crh) cytoplasm (Crh)
Anatomy Link Frequency
ovary 2
Crh (Rattus norvegicus)
Gnrh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 1 92.88 High High
Serotonin 1 92.16 High High
5HT 3 91.28 High High
Lasting pain 2 89.36 High High
Fibrositis 10 84.88 Quite High
Central nervous system 3 69.28 Quite High
Acupuncture 56 54.96 Quite High
depression 1 45.20 Quite Low
Pain 2 44.24 Quite Low
c fibre 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Polycystic Ovary Syndrome 62 92.56 High High
Pain 3 89.36 High High
Stress 2 86.72 High High
Fibromyalgia 8 84.88 Quite High
Apoptosis 1 73.76 Quite High
Metabolic Disorder 1 68.08 Quite High
Syndrome 2 66.28 Quite High
Insulin Resistance 1 65.12 Quite High
Hyperinsulinism 1 64.16 Quite High
Obesity 1 63.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Corticotropin-releasing hormone (CRH) may also modulate GnRH release [5] and thus may be involved in the neuroendocrine dysfunction.
CRH Spec (may) Regulation (modulate) of Localization (release) of GnRH
1) Confidence 0.36 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722078 Disease Relevance 1.25 Pain Relevance 0.05
The lowered oestrogen levels could be accounted for both via an inhibitory effect of the CRH on the hypothalamic release of LHRH or via a direct CRH-mediated inhibition of the FSH-stimulated oestrogen production in the ovary.
CRH Regulation (effect) of Localization (release) of LHRH in ovary
2) Confidence 0.01 Published 2000 Journal Scand. J. Rheumatol. Suppl. Section Abstract Doc Link 11028824 Disease Relevance 0.53 Pain Relevance 0.56

General Comments

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