INT91416

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.40
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 1.88
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (PTGES) signal transduction (PTGES) cytoplasm (PTGES)
PTGES (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 6 100.00 Very High Very High Very High
dexamethasone 1 99.50 Very High Very High Very High
Inflammation 3 95.24 Very High Very High Very High
cINOD 5 85.44 High High
Dismenorea 1 65.96 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 11 100.00 Very High Very High Very High
Necrosis 1 96.28 Very High Very High Very High
INFLAMMATION 6 95.24 Very High Very High Very High
Colon Cancer 2 77.72 Quite High
Toxicity 2 73.92 Quite High
Dysmenorrhea 1 65.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
mPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators".
Negative_regulation (suppression) of Positive_regulation (mediators) of mPGES-1 associated with cancer
1) Confidence 0.40 Published 2010 Journal Biochimie Section Title Doc Link 20159031 Disease Relevance 0.73 Pain Relevance 0.21
mPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators".
Negative_regulation (review) of Positive_regulation (mediators) of mPGES-1 associated with cancer
2) Confidence 0.40 Published 2010 Journal Biochimie Section Title Doc Link 20159031 Disease Relevance 0.73 Pain Relevance 0.21
PTGES induction was blocked both in the presence of pharmacological NFkappaB inhibitors and following adenovirus-mediated overexpression of a dominant-negative NFkappaB pathway protein.
Negative_regulation (blocked) of Positive_regulation (induction) of PTGES
3) Confidence 0.35 Published 2008 Journal Biol. Reprod. Section Abstract Doc Link 17928629 Disease Relevance 0.13 Pain Relevance 0.22
Dexamethasone was found to completely suppress the effect of both cytokines on PGES induction.
Negative_regulation (suppress) of Positive_regulation (induction) of PGES associated with dexamethasone and cytokine
4) Confidence 0.22 Published 2000 Journal Eur. J. Biochem. Section Abstract Doc Link 11029586 Disease Relevance 0.28 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox