INT91508

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Context Info
Confidence 0.49
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 6
Disease Relevance 3.76
Pain Relevance 1.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (CYC1) mitochondrion (CYC1) small molecule metabolic process (CYC1)
cytoplasm (CYC1)
Anatomy Link Frequency
HL-60 4
acinar cells 4
liver 2
Raji 1
MOLT-4 1
CYC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 21 98.58 Very High Very High Very High
Cannabinoid receptor 1 90.48 High High
Spinal cord 1 87.56 High High
cINOD 3 86.20 High High
Inflammation 1 78.76 Quite High
pain suppression 1 78.08 Quite High
Glutamate 1 68.80 Quite High
chemokine 4 55.88 Quite High
Chronic pancreatitis 2 52.80 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 31 98.22 Very High Very High Very High
Death 8 91.92 High High
INFLAMMATION 4 85.96 High High
Pain 1 78.08 Quite High
Injury 4 75.00 Quite High
Parkinson's Disease 2 75.00 Quite High
Pancreatitis 4 52.80 Quite High
Pressure And Volume Under Development 1 52.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The apoptotic effect of aspirin was analyzed in different cell lines (Jurkat, MOLT-4, Raji and HL-60) showing induction of mitochondrial cytochrome c release and caspases 9, 3 and 8 processing.
Positive_regulation (induction) of Gene_expression (showing) of cytochrome c in HL-60 associated with aspirin and apoptosis
1) Confidence 0.49 Published 2000 Journal FEBS Lett. Section Abstract Doc Link 11034327 Disease Relevance 0.44 Pain Relevance 0.35
N-arachidonylglycine causes ROS production and cytochrome c release in liver mitochondria.
Positive_regulation (causes) of Gene_expression (production) of cytochrome c in liver
2) Confidence 0.45 Published 2009 Journal Free Radic. Biol. Med. Section Title Doc Link 19501648 Disease Relevance 0.21 Pain Relevance 0.24
The change of Psim by 50% was observed in the presence of CXCL10 in treated acinar cells along with enhanced expression of Cytochrome C, apaf-1 and caspase 9/3 activation.
Positive_regulation (activation) of Gene_expression (expression) of Cytochrome C in acinar cells
3) Confidence 0.45 Published 2010 Journal Int J Exp Pathol Section Abstract Doc Link 20041963 Disease Relevance 1.11 Pain Relevance 0.08
The change of Psim by 50% was observed in the presence of CXCL10 in treated acinar cells along with enhanced expression of Cytochrome C, apaf-1 and caspase 9/3 activation.
Positive_regulation (enhanced) of Gene_expression (expression) of Cytochrome C in acinar cells
4) Confidence 0.45 Published 2010 Journal Int J Exp Pathol Section Abstract Doc Link 20041963 Disease Relevance 1.11 Pain Relevance 0.08
The apoptotic effect of aspirin was analyzed in different cell lines (Jurkat, MOLT-4, Raji and HL-60) showing induction of mitochondrial cytochrome c release and caspases 9, 3 and 8 processing.
Positive_regulation (induction) of in MOLT-4 Gene_expression (showing) of cytochrome c in HL-60 associated with aspirin and apoptosis
5) Confidence 0.17 Published 2000 Journal FEBS Lett. Section Abstract Doc Link 11034327 Disease Relevance 0.44 Pain Relevance 0.35
The apoptotic effect of aspirin was analyzed in different cell lines (Jurkat, MOLT-4, Raji and HL-60) showing induction of mitochondrial cytochrome c release and caspases 9, 3 and 8 processing.
Positive_regulation (induction) of in Raji Gene_expression (showing) of cytochrome c in HL-60 associated with aspirin and apoptosis
6) Confidence 0.17 Published 2000 Journal FEBS Lett. Section Abstract Doc Link 11034327 Disease Relevance 0.44 Pain Relevance 0.35

General Comments

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