INT91665

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Context Info
Confidence 0.48
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.27
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CASP1) peptidase activity (CASP1) signal transduction (CASP1)
intracellular (CASP1) cytoplasm (CASP1)
CASP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 8 99.16 Very High Very High Very High
cytokine 4 84.68 Quite High
Inflammation 9 64.16 Quite High
cINOD 2 53.80 Quite High
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 75.00 Quite High
Fever 11 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Syndrome 9 5.00 Very Low Very Low Very Low
Osteomyelitis 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Acne 2 5.00 Very Low Very Low Very Low
Pyoderma Gangrenosum 2 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NCX-4016, but not aspirin, prevented ICE activation as measured by assessing the release of ICE p20 subunit.
Positive_regulation (assessing) of Localization (release) of ICE associated with aspirin
1) Confidence 0.48 Published 2000 Journal J. Immunol. Section Abstract Doc Link 11046058 Disease Relevance 0.20 Pain Relevance 0.37
This, in turn, leads to multimerization of ASC and subsequent recruitment and activation of Caspase-1.
Positive_regulation (activation) of Localization (recruitment) of Caspase-1
2) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2702820 Disease Relevance 0.06 Pain Relevance 0.03

General Comments

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