INT91666

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Context Info
Confidence 0.02
First Reported 2000
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.25
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (SLC8A1) plasma membrane (SLC8A1) transmembrane transport (SLC8A1)
Anatomy Link Frequency
monocytes 1
nerves 1
sympathetic 1
SLC8A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 8 100.00 Very High Very High Very High
cytokine 4 100.00 Very High Very High Very High
Neurotransmitter 6 99.96 Very High Very High Very High
cINOD 2 96.80 Very High Very High Very High
noradrenaline 4 96.12 Very High Very High Very High
cocaine 2 90.56 High High
agonist 2 89.36 High High
tetrodotoxin 2 82.56 Quite High
conotoxin 2 70.92 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 95.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we tested the hypothesis that NCX-4016, a NO-aspirin derivative, inhibits proinflammatory cytokine release from endotoxin (LPS)-challenged monocytes.
Localization (release) of NCX-4016 in monocytes associated with aspirin and cytokine
1) Confidence 0.02 Published 2000 Journal J. Immunol. Section Abstract Doc Link 11046058 Disease Relevance 0.25 Pain Relevance 0.39
It is concluded that after blockade of VSCCs brief depolarising pulses may reverse Na+/Ca2+-exchange and release neurotransmitter in Na+-loaded sympathetic nerves.
Localization (release) of Na+/Ca2+-exchange in nerves associated with neurotransmitter
2) Confidence 0.02 Published 2004 Journal Neurochem. Int. Section Abstract Doc Link 15234113 Disease Relevance 0 Pain Relevance 0.18
Presynaptic alpha2-receptors regulate reverse Na+/Ca2+-exchange and transmitter release in Na+-loaded peripheral sympathetic nerves.
Localization (release) of Na+/Ca2+-exchange in sympathetic
3) Confidence 0.02 Published 2004 Journal Neurochem. Int. Section Title Doc Link 15234113 Disease Relevance 0 Pain Relevance 0.25

General Comments

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