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Context Info
Confidence 0.23
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) aging (Il6) extracellular region (Il6)
plasma membrane (Oprd1) cytoplasm (Oprd1) signal transducer activity (Oprd1)
Anatomy Link Frequency
Sertoli cells 1
Il6 (Rattus norvegicus)
Oprd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 2 100.00 Very High Very High Very High
opioid receptor 3 92.96 High High
cytokine 2 91.32 High High
Opioid 3 80.88 Quite High
Central nervous system 3 72.92 Quite High
Endogenous opioid 1 69.92 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a semiquantitative PCR analysis using the S16 ribosomal RNA gene as an internal control, we show that interleukin-6 reduces kappa opioid receptor mRNA levels from 6 to 24 h of treatment in primary Sertoli cells.
interleukin-6 Negative_regulation (reduces) of opioid receptor mRNA in Sertoli cells associated with kappa opioid receptor
1) Confidence 0.23 Published 2000 Journal Endocrine Section Abstract Doc Link 11051042 Disease Relevance 0 Pain Relevance 0.70

General Comments

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