INT91784

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Context Info
Confidence 0.45
First Reported 2000
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.38
Pain Relevance 1.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr1a) signal transducer activity (Htr1a)
Anatomy Link Frequency
spinal cord 2
DRN 2
Htr1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 1 100.00 Very High Very High Very High
Inflammation 9 99.88 Very High Very High Very High
Pain 3 95.04 Very High Very High Very High
Spontaneous pain 2 89.84 High High
spinal dorsal horn 1 89.84 High High
Hyperalgesia 4 89.76 High High
Central grey 2 85.08 High High
allodynia 1 85.00 Quite High
Raphe 2 83.00 Quite High
IPN 2 76.00 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 5 99.88 Very High Very High Very High
Pain 3 95.04 Very High Very High Very High
Nociception 1 91.68 High High
Hyperalgesia 4 89.76 High High
Urological Neuroanatomy 2 85.08 High High
Neuropathic Pain 1 85.00 Quite High
Inflammatory Pain 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following carrageenan inflammation, the expression of 5-HT1A receptor mRNA in the DRN and bilateral vlPAG neurons was significantly increased.
Positive_regulation (increased) of Transcription (expression) of 5-HT1A in DRN associated with inflammation
1) Confidence 0.45 Published 2000 Journal Neuroreport Section Abstract Doc Link 11059903 Disease Relevance 0.42 Pain Relevance 0.36
Here we showed that 1 or 4 h after a subcutaneous bee venom challenge, expression of 5-HT1A receptor mRNA in the ipsilateral lumbar spinal cord increased significantly by 80.94 or 37.86%, respectively.
Positive_regulation (increased) of Transcription (expression) of 5-HT1A in spinal cord associated with spinal cord
2) Confidence 0.45 Published 2003 Journal Pain Section Abstract Doc Link 14581120 Disease Relevance 0.95 Pain Relevance 0.94

General Comments

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