INT9180

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Context Info
Confidence 0.24
First Reported 1990
Last Reported 1995
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.25
Pain Relevance 2.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrh, Gh) extracellular region (Ghrh, Gh) cytosol (Gh)
signal transduction (Gh) mitochondrion (Gh) plasma membrane (Gh)
Ghrh (Rattus norvegicus)
Gh (Mus musculus)
Pain Link Frequency Relevance Heat
Clonidine 19 100.00 Very High Very High Very High
Sumatriptan 10 100.00 Very High Very High Very High
agonist 3 100.00 Very High Very High Very High
Somatostatin 3 98.08 Very High Very High Very High
Serotonin 2 80.40 Quite High
Disease Link Frequency Relevance Heat
Obesity 2 99.84 Very High Very High Very High
Endocrine Disease 1 98.28 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The aim of our study was to evaluate the effects of GH-releasing hormone (GHRH) and clonidine, an alpha-2-adrenergic agonist which increases GH secretion acting at the hypothalamic level with an unknown mechanism, on GH secretion in seven adult patients (3M, 4F) with non endocrine diseases and on daily immunosuppressive glucocorticoid therapy.
GHRH Regulation (effects) of Localization (secretion) of GH associated with endocrine disease, agonist and clonidine
1) Confidence 0.24 Published 1992 Journal Horm. Metab. Res. Section Abstract Doc Link 1398465 Disease Relevance 0.10 Pain Relevance 0.40
Unexpectedly, we found that five of the 21 (26%) normal controls had no GH secretory response to either GRF or clonidine.
GRF Neg (no) Regulation (response) of Neg (no) Localization (secretory) of GH associated with clonidine
2) Confidence 0.12 Published 1990 Journal Psychoneuroendocrinology Section Abstract Doc Link 2087535 Disease Relevance 0 Pain Relevance 1.06
Furthermore, we assessed the effect of Sumatriptan on basal GH secretion and the GH response to GHRH in obese children.
GHRH Regulation (effect) of Localization (secretion) of GH associated with sumatriptan and obesity
3) Confidence 0.02 Published 1995 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 7775648 Disease Relevance 0.15 Pain Relevance 0.72

General Comments

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