INT91820

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Context Info
Confidence 0.44
First Reported 2000
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.03
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGA2B) plasma membrane (ITGA2B)
Anatomy Link Frequency
platelet 2
CD14 1
ITGA2B (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 6 83.24 Quite High
Angina 7 82.16 Quite High
Disease Link Frequency Relevance Heat
Syndrome 5 98.44 Very High Very High Very High
Stroke 6 86.28 High High
Thrombosis 8 86.08 High High
Myocardial Infarction 6 85.84 High High
Acute Coronary Syndrome 2 84.24 Quite High
Cv General 3 Under Development 7 82.16 Quite High
Increased Venous Pressure Under Development 2 76.68 Quite High
Adhesions 2 75.56 Quite High
Rupture 1 73.56 Quite High
Cardiovascular Disease 2 30.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The past several years have seen the introduction of many platelet GPIIb/IIIa blockers into the clinical arena targeting the unique platelet GPIIb/IIIa receptor for the adhesive proteins, fibrinogen and von Willebrand Factor.
Regulation (introduction) of GPIIb in platelet
1) Confidence 0.44 Published 2000 Journal Expert Opin Investig Drugs Section Abstract Doc Link 11060829 Disease Relevance 0.94 Pain Relevance 0.16
The past several years have seen the introduction of many platelet GPIIb/IIIa blockers into the clinical arena targeting the unique platelet GPIIb/IIIa receptor for the adhesive proteins, fibrinogen and von Willebrand Factor.
Regulation (targeting) of GPIIb in platelet
2) Confidence 0.26 Published 2000 Journal Expert Opin Investig Drugs Section Abstract Doc Link 11060829 Disease Relevance 0.94 Pain Relevance 0.16
RESULTS: PTCA induced a marked up-regulation of CD18, CD11b, CD14 and GPIIb/IIIa with L-selectin shedding and reduced SO formation, whereas only minor L-selectin down-regulation and decreased SO production indicated activation in UA.
Regulation (regulation) of GPIIb in CD14
3) Confidence 0.26 Published 2005 Journal Int. J. Cardiol. Section Body Doc Link 15771923 Disease Relevance 0.15 Pain Relevance 0

General Comments

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