INT91832

Context Info Confidence 0.01 First Reported 2000 Last Reported 2000 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0

plasma membrane (CD81, Hbegf) cell proliferation (CD81) extracellular space (Hbegf) extracellular region (Hbegf)

Anatomy Link Frequency bladder 2 CD81 (Homo sapiens) Hbegf (Rattus norvegicus)

Pain Link Frequency Relevance Heat interstitial cystitis 6 50.00

Disease Link Frequency Relevance Heat Interstitial Cystitis 6 70.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Purified antiproliferative factor specifically inhibited HB-EGF production by bladder epithelial cells in vitro, and the effect of interstitial cystitis urine or purified antiproliferative factor on bladder cell proliferation was inhibited by recombinant human HB-EGF in a dose dependent manner.

antiproliferative factor Negative_regulation (inhibited) of Gene_expression (production) of HB-EGF in bladder

1) Confidence 0.01 Published 2000 Journal J. Urol. Section Body Doc Link 11061938 Disease Relevance 0.07 Pain Relevance 0

General Comments

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