INT91866

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Context Info
Confidence 0.69
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RPA1) chromosome organization (RPA1) nucleolus (RPA1)
nucleus (RPA1) DNA binding (RPA1) cytoplasm (RPA1)
Anatomy Link Frequency
endothelial cells 2
RPA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 2 76.72 Quite High
Disease Link Frequency Relevance Heat
Myocardial Infarction 1 77.76 Quite High
Cv General 3 Under Development 2 76.72 Quite High
Spasticity 2 76.44 Quite High
Coronary Artery Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In human umbilical vein endothelial cells, inhibition of RPA1 expression using antisense oligonucleotide restored transcription driven by the mutated promoter sequence, whereas, conversely, overexpression of RPA1 further reduced it.
Positive_regulation (overexpression) of Gene_expression (overexpression) of RPA1 in endothelial cells
1) Confidence 0.69 Published 2000 Journal Hum. Mol. Genet. Section Abstract Doc Link 11063722 Disease Relevance 0.38 Pain Relevance 0.15

General Comments

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