INT919

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.47
First Reported 1979
Last Reported 1995
Negated 3
Speculated 1
Reported most in Abstract
Documents 7
Total Number 8
Disease Relevance 1.09
Pain Relevance 2.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GH1) extracellular region (GH1)
Anatomy Link Frequency
plasma 2
thyroid 2
GH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 20 100.00 Very High Very High Very High
narcan 8 100.00 Very High Very High Very High
opiate 3 100.00 Very High Very High Very High
Delta opioid receptors 6 96.24 Very High Very High Very High
agonist 4 91.44 High High
opioid receptor 4 91.12 High High
Opioid 3 89.32 High High
Somatostatin 1 68.96 Quite High
peptic ulcer disease 2 65.68 Quite High
Central nervous system 1 50.64 Quite High
Disease Link Frequency Relevance Heat
Hypotension 1 99.68 Very High Very High Very High
Endometriosis (extended) 1 99.52 Very High Very High Very High
Hypertension 3 97.52 Very High Very High Very High
Hypoglycemia 7 96.88 Very High Very High Very High
Disease 2 65.68 Quite High
Ulcers 2 65.36 Quite High
Gynecomastia 1 53.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study the effect of the opiate receptor blocker naloxone on the increase in plasma GH induced by clonidine was investigated in eight patients with essential hypertension.
Regulation (effect) of Positive_regulation (increase) of GH in plasma associated with hypertension, narcan, opiate and clonidine
1) Confidence 0.47 Published 1984 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 6319449 Disease Relevance 0.17 Pain Relevance 0.87
To investigate the possible mechanism leading to the decrease in GH secretion by specific activation of delta-opioidergic pathway in man, we compared, in normal subjects, the effect of DT on GH secretion responses to two different GH secretagogues, namely arginine (ARG) and galanin (GAL).
Regulation (effect) of Positive_regulation (responses) of GH
2) Confidence 0.44 Published 1995 Journal Regul. Pept. Section Abstract Doc Link 8570858 Disease Relevance 0 Pain Relevance 0.21
DT blunted the GH response to IIH, whereas it had no effect on the GH response to GHRH.
Neg (no) Regulation (effect) of Positive_regulation (response) of GH
3) Confidence 0.40 Published 1992 Journal Neuroendocrinology Section Abstract Doc Link 1369601 Disease Relevance 0.17 Pain Relevance 0.33
Based on the lack of an effect of DT on the GH response to GHRH, we suggest that DT may modulate the secretion of GH through suprapituitary mechanisms.
Regulation (effect) of Positive_regulation (response) of GH
4) Confidence 0.40 Published 1992 Journal Neuroendocrinology Section Abstract Doc Link 1369601 Disease Relevance 0.16 Pain Relevance 0.32
To investigate the effect of co-treatment with growth hormone (GH) for ovulation induction with human menopausal gonadotrophins (HMG) on conception, we compared the pregnancy rate and response to co-treatment with GH versus HMG/human chorionic gonadotrophin (HCG) alone in a prospective, randomized, cross-over protocol of ovulation induction for either in-vivo or in-vitro fertilization (IVF).
Spec (investigate) Regulation (effect) of Spec (investigate) Positive_regulation (induction) of GH associated with endometriosis (extended)
5) Confidence 0.37 Published 1994 Journal Hum. Reprod. Section Abstract Doc Link 8027274 Disease Relevance 0.10 Pain Relevance 0.21
The effect of clonidine (0.15 mg i.v.) on circulating GH, glucagon and glucose concentrations was measured in six normal subjects.
Regulation (effect) of Positive_regulation (circulating) of GH associated with clonidine
6) Confidence 0.22 Published 1981 Journal Horm. Metab. Res. Section Abstract Doc Link 7308974 Disease Relevance 0 Pain Relevance 0.34
This GH increase was independent of the hypotensive effect of the drug and was observed without any modification of plasma prolactin, thyroid stimulating hormone, gonadotropins and glycemia.
Neg (independent) Regulation (independent) of Positive_regulation (increase) of GH in thyroid associated with hypotension
7) Confidence 0.20 Published 1979 Journal J. Endocrinol. Invest. Section Abstract Doc Link 119798 Disease Relevance 0.10 Pain Relevance 0.34
Cimetidine had no effect on the GH, PRL, or cortisol response to insulin-induced hypolycemia or the 24-h secretion of LH, FSH, testosterone, or PRL.
Neg (no) Regulation (effect) of Positive_regulation (response) of GH
8) Confidence 0.17 Published 1979 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 113425 Disease Relevance 0.38 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox