INT91907

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Context Info
Confidence 0.48
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.37
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il10) extracellular region (Il10) intracellular (Il10)
Anatomy Link Frequency
macrophages 2
Il10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 35 92.40 High High
Spinal cord 2 90.80 High High
Neurotransmitter 1 87.60 High High
Sciatic nerve 2 82.96 Quite High
Dorsal horn 3 82.80 Quite High
cytokine 23 82.16 Quite High
Enkephalin 2 75.00 Quite High
allodynia 1 65.44 Quite High
Thermal hyperalgesia 1 64.44 Quite High
Neuropathic pain 1 48.56 Quite Low
Disease Link Frequency Relevance Heat
Injury 7 99.82 Very High Very High Very High
INFLAMMATION 38 92.40 High High
Nervous System Injury 4 85.80 High High
Cancer 3 75.00 Quite High
Neuropathic Pain 3 75.00 Quite High
Necrosis 2 75.00 Quite High
Urological Neuroanatomy 12 68.44 Quite High
Hyperalgesia 1 64.44 Quite High
Weight Loss 4 62.72 Quite High
Diarrhoea 1 61.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recruitment of epineurial IL-10 immunoreactive macrophages as well as the recovery of injury-induced depletion of endoneurial IL-10-IR was enhanced by thalidomide treatment.
Positive_regulation (enhanced) of Negative_regulation (depletion) of IL-10-IR in macrophages associated with injury
1) Confidence 0.48 Published 2000 Journal Pain Section Abstract Doc Link 11068114 Disease Relevance 0.89 Pain Relevance 0.78
In fact, a linear correlation test between these variables was performed and a strong association between an increase in IL-10 and decrease in DNA damage (r = 0.77) was found (Figure 3).


Positive_regulation (increase) of Negative_regulation (decrease) of IL-10
2) Confidence 0.19 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2909993 Disease Relevance 0.48 Pain Relevance 0.22

General Comments

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