INT91926

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Context Info
Confidence 0.08
First Reported 2000
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.95
Pain Relevance 1.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Kcnab3) cytoplasm (Kcnab3)
Anatomy Link Frequency
DRG 2
Kcnab3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 6 100.00 Very High Very High Very High
Neuropathic pain 5 98.68 Very High Very High Very High
diabetic neuropathy 2 98.52 Very High Very High Very High
Eae 2 97.64 Very High Very High Very High
Spinal cord 6 90.24 High High
dorsal root ganglion 5 88.24 High High
Abeta 1 86.08 High High
c fibre 2 76.64 Quite High
substantia gelatinosa 1 74.68 Quite High
Adelta 1 59.04 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 5 98.68 Very High Very High Very High
Diabetic Neuropathy 2 98.52 Very High Very High Very High
Injury 2 97.64 Very High Very High Very High
Ganglion Cysts 5 87.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study we have used in situ hybridization to examine the changes in mRNA expression of the voltage gated sodium channel subunits beta1 and beta3, which occur in response to streptozocin induced diabetic neuropathy.
Positive_regulation (occur) of Transcription (expression) of beta3 associated with diabetic neuropathy and sodium channel
1) Confidence 0.08 Published 2001 Journal Neurosci. Lett. Section Abstract Doc Link 11489532 Disease Relevance 0.60 Pain Relevance 0.71
Results revealed a significant increase in beta3 mRNA expression in small-diameter sensory neurons of the ipsilateral DRG.
Positive_regulation (increase) of Transcription (expression) of beta3 in DRG
2) Confidence 0.03 Published 2000 Journal Eur. J. Neurosci. Section Abstract Doc Link 11069594 Disease Relevance 0.35 Pain Relevance 0.63

General Comments

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