INT91949

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Context Info
Confidence 0.44
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prkce) Golgi apparatus (Prkce) endoplasmic reticulum (Prkce)
enzyme binding (Prkce) cytoplasm (Prkce) cytosol (Prkce)
Anatomy Link Frequency
nociceptors 2
Prkce (Rattus norvegicus)
Pain Link Frequency Relevance Heat
alcohol 5 99.52 Very High Very High Very High
nociceptor 2 98.76 Very High Very High Very High
Hyperalgesia 3 97.00 Very High Very High Very High
Kinase C 2 91.48 High High
Action potential 1 85.96 High High
c fibre 1 83.20 Quite High
allodynia 1 81.12 Quite High
Thermal hyperalgesia 1 80.12 Quite High
Pain 2 75.00 Quite High
Neuropathic pain 1 68.88 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 4 97.00 Very High Very High Very High
Nociception 1 94.56 High High
Neuropathic Pain 2 81.12 Quite High
Alcoholic Neuropathy 1 75.00 Quite High
Peripheral Neuropathy 1 61.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Western immunoblot analysis indicated a higher level of PKCepsilon in dorsal root ganglia from alcohol-fed rats, supporting a role for enhanced PKCepsilon second-messenger signaling in nociceptors contributing to alcohol-induced hyperalgesia.
Regulation (role) of Positive_regulation (enhanced) of PKCepsilon in nociceptors associated with hyperalgesia, nociceptor and alcohol
1) Confidence 0.44 Published 2000 Journal J. Neurosci. Section Abstract Doc Link 11069970 Disease Relevance 0.72 Pain Relevance 1.24

General Comments

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