INT91991

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.57
First Reported 2000
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 2.55
Pain Relevance 1.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
proximal 1
neutrophils 1
IGKV1-22 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 1 99.68 Very High Very High Very High
iatrogenic 4 99.54 Very High Very High Very High
cINOD 10 98.52 Very High Very High Very High
depression 224 92.44 High High
deep brain stimulation 24 88.32 High High
Hippocampus 8 88.08 High High
Inflammatory response 1 79.32 Quite High
Nucleus accumbens 56 74.96 Quite High
Dopamine 20 72.32 Quite High
amygdala 92 61.56 Quite High
Disease Link Frequency Relevance Heat
Bronchopulmonary Dysplasia 4 99.34 Very High Very High Very High
Manic Depressive Disorder 32 99.24 Very High Very High Very High
Repression 160 98.88 Very High Very High Very High
Depression 288 98.70 Very High Very High Very High
Cicatrix 4 92.00 High High
Attention Deficit Hyperactivity Disorder 32 86.48 High High
Neurosis 16 83.24 Quite High
INFLAMMATION 3 82.44 Quite High
Treatment-resistant Depression (TRD) 16 76.68 Quite High
Adhesions 1 75.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment of neutrophils either with Ro 31-8220 and H7, 2 specific inhibitors of protein kinase C (PKC), or with inhibitors of protein tyrosine kinases such as tyrphostin A25 or herbimycin A did not prevent the NSAID-mediated L-selectin shedding.
Negative_regulation (inhibitors) of A25 in neutrophils associated with kinase c and cinod
1) Confidence 0.57 Published 2000 Journal Blood Section Abstract Doc Link 11071659 Disease Relevance 0.31 Pain Relevance 0.85
Postmortem and MRI studies have found glial loss and volume reductions in the PFC in major depressive disorder (MDD) and bipolar disorder (BPD) [209-214] as well as extensive losses in Cg25 and proximal paralimbic regions [163,201,215-221].
Negative_regulation (losses) of Cg25 in proximal associated with manic depressive disorder, depression and bronchopulmonary dysplasia
2) Confidence 0.08 Published 2008 Journal Ann Gen Psychiatry Section Body Doc Link PMC2515304 Disease Relevance 0.74 Pain Relevance 0.27
Spontaneous and treatment-induced remission of symptoms is associated with significantly decreased Cg25 metabolism [51,100,105,110,113,116-119].
Negative_regulation (decreased) of Cg25
3) Confidence 0.06 Published 2008 Journal Ann Gen Psychiatry Section Body Doc Link PMC2515304 Disease Relevance 0.53 Pain Relevance 0.29
If the ego is dependent on repression, we would expect to see decreased activity in the DMN, decreased activity in Cg25 and increased activity in the ON after stimulation.
Negative_regulation (decreased) of Cg25 associated with repression
4) Confidence 0.06 Published 2008 Journal Ann Gen Psychiatry Section Body Doc Link PMC2515304 Disease Relevance 0.46 Pain Relevance 0.13
One possible reason why the effect of Cg25 stimulation appears to have a sustained beneficial effect [253] rather than an iatrogenic one [254] may be that inhibiting activity in Cg25 facilitates the disintegration of a wider network.
Negative_regulation (inhibiting) of Cg25 associated with iatrogenic
5) Confidence 0.06 Published 2008 Journal Ann Gen Psychiatry Section Body Doc Link PMC2515304 Disease Relevance 0.50 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox