INT92127

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Context Info
Confidence 0.40
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.66
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Thbd) plasma membrane (Thbd) embryo development (Thbd)
Anatomy Link Frequency
endothelial cell 2
vessels 2
Thbd (Mus musculus)
Pain Link Frequency Relevance Heat
aspirin 156 99.70 Very High Very High Very High
Inflammation 51 87.80 High High
cva 9 85.84 High High
Pain 3 25.00 Low Low
cINOD 8 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myositis 1 88.16 High High
Dermatomyositis 2 87.84 High High
Cv General 3 Under Development 4 85.84 High High
Myalgia 1 83.00 Quite High
Stomach Cancer 2 82.04 Quite High
Frailty 1 80.80 Quite High
Atherosclerosis 70 80.76 Quite High
INFLAMMATION 56 76.60 Quite High
Hemorrhage 4 73.96 Quite High
Malignant Neoplastic Disease 2 72.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemical analysis of procoagulant or anticoagulant factors revealed marked reduction of thrombomodulin (TM) expression on small vessels and capillaries.
Negative_regulation (reduction) of Gene_expression (expression) of thrombomodulin in vessels
1) Confidence 0.40 Published 2000 Journal Acta Neuropathol. Section Abstract Doc Link 11078226 Disease Relevance 1.00 Pain Relevance 0.09
High dose ASA, but not NCX 4016, inhibited endothelial cell expression of VCAM-1 and thrombomodulin in the carotid arteries at 4 weeks after irradiation; eNOS and ICAM-1 levels were unchanged.
Negative_regulation (inhibited) of Gene_expression (expression) of thrombomodulin in endothelial cell
2) Confidence 0.32 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2943480 Disease Relevance 0.53 Pain Relevance 0.28
High dose ASA resulted in a decreased expression of thrombomodulin at the bifurcation compared with control mice (p?
Negative_regulation (decreased) of Gene_expression (expression) of thrombomodulin associated with aspirin
3) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943480 Disease Relevance 0.14 Pain Relevance 0.27

General Comments

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