INT92318

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Context Info
Confidence 0.26
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CALCA, IL6) aging (CALCA, IL6) extracellular region (CALCA, IL6)
nucleus (CALCA) intracellular (CALCA) cell-cell signaling (CALCA)
Anatomy Link Frequency
fibroblasts 2
CALCA (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neurotransmitter 3 50.00 Quite Low
rheumatoid arthritis 2 50.00 Quite Low
Osteoarthritis 2 50.00 Quite Low
adenocard 1 5.00 Very Low Very Low Very Low
Enkephalin 1 5.00 Very Low Very Low Very Low
calcitonin gene related peptide 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
substance P 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 2 87.56 High High
Rheumatoid Arthritis 3 86.44 High High
Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: In RA fibroblasts, CGRP increased IL-6 and IL-8 secretion at 10(-10) to 10(-8) M (p at least < 0.01), which was not observed in OA fibroblasts.
CGRP Positive_regulation (increased) of Localization (secretion) of IL-6 in fibroblasts
1) Confidence 0.26 Published 2000 Journal J. Rheumatol. Section Body Doc Link 11093434 Disease Relevance 0.26 Pain Relevance 0

General Comments

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