INT92426

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Context Info
Confidence 0.58
First Reported 2000
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 10
Total Number 10
Disease Relevance 6.14
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lymph nodes 1
pancreas 1
Ts1 (Mus musculus)
Pain Link Frequency Relevance Heat
abdominal pain 3 97.08 Very High Very High Very High
palliative 4 92.12 High High
Pain 2 88.92 High High
backache 1 38.56 Quite Low
methotrexate 1 38.24 Quite Low
imagery 11 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
positron emission tomography 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stomach Cancer 53 100.00 Very High Very High Very High
Duodenal Neoplasms 1 99.50 Very High Very High Very High
Metastasis 34 98.42 Very High Very High Very High
Cecal Neoplasms 1 98.12 Very High Very High Very High
Colon Cancer 1 98.10 Very High Very High Very High
Abdominal Pain 3 97.08 Very High Very High Very High
Vomiting 4 96.44 Very High Very High Very High
Weight Loss 1 95.88 Very High Very High Very High
Esophageal Cancer 34 93.80 High High
Cancer 68 93.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TS-1 is an oral anticancer drug that produces biochemical modulation.
Gene_expression (produces) of TS-1
1) Confidence 0.58 Published 2000 Journal Gan To Kagaku Ryoho Section Abstract Doc Link 11103250 Disease Relevance 0.15 Pain Relevance 0
[Utility-based evaluation of the quality of life of patient's with gastric cancer who receive chemotherapy--comparison of patients' quality of life between oral TS-1 and conventional injectable combination therapy].
Gene_expression (evaluation) of TS-1 associated with stomach cancer
2) Confidence 0.57 Published 2008 Journal Yakugaku Zasshi Section Title Doc Link 18451627 Disease Relevance 0.28 Pain Relevance 0.09
[A case of peritoneal dissemination of postoperative primary duodenal cancer successfully treated by TS-1 therapy].
Gene_expression (therapy) of TS-1 associated with duodenal neoplasms
3) Confidence 0.57 Published 2005 Journal Gan To Kagaku Ryoho Section Title Doc Link 16121925 Disease Relevance 1.01 Pain Relevance 0.10
[Sustained NC status for a long period after combined chemotherapy of TS-1 and CDDP for residual lesions following gastrectomy for gastric cancer].
Gene_expression (chemotherapy) of TS-1 associated with stomach cancer
4) Confidence 0.56 Published 2003 Journal Gan To Kagaku Ryoho Section Title Doc Link 12795103 Disease Relevance 0.45 Pain Relevance 0.09
[A case of advanced gastric cancer with invasion of pancreas effectively treated by combined chemotherapy of TS-1 and paclitaxel (TXL)].
Gene_expression (chemotherapy) of TS-1 in pancreas associated with stomach cancer
5) Confidence 0.50 Published 2002 Journal Gan To Kagaku Ryoho Section Title Doc Link 12355952 Disease Relevance 0.76 Pain Relevance 0.07
[A case of advanced colon cancer with metastases to both para-aortic lymph nodes and cervical vertebrae effectively treated by TS-1 therapy].
Gene_expression (therapy) of TS-1 in lymph nodes associated with colon cancer and metastasis
6) Confidence 0.49 Published 2006 Journal Gan To Kagaku Ryoho Section Title Doc Link 16612166 Disease Relevance 0.72 Pain Relevance 0.09
[Usefulness of TS-1 and lentinan combination immunochemotherapy in advanced or recurrent gastric cancer--pilot study aiming at a randomized trial].
Gene_expression ([Usefulness) of TS-1 associated with stomach cancer
7) Confidence 0.35 Published 2003 Journal Gan To Kagaku Ryoho Section Title Doc Link 12938267 Disease Relevance 0.64 Pain Relevance 0.06
Several combinations such as low dose cisplatin (CDDP) + protracted infusional 5-fluorouracil(5-FU), leucoborin(IN) + 5-FU, weekly taxane and oral chemotherapy(TS-1) produce objective response in 30-50% of patients, and who get PR can actually enjoy improved QOL during the remission.
Gene_expression (produce) of TS-1
8) Confidence 0.18 Published 2003 Journal Nippon Rinsho Section Abstract Doc Link 12806953 Disease Relevance 0.34 Pain Relevance 0.09
Joshi et al., measured gene expressions of thymidylate synthase 1 (TS1), glutathione S-transferase ?
Gene_expression (expressions) of TS1
9) Confidence 0.08 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1999497 Disease Relevance 0.61 Pain Relevance 0
In our patient, we first used TS-1 and paclitaxel combination chemotherapy.
Gene_expression (used) of TS-1
10) Confidence 0.05 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1939849 Disease Relevance 1.17 Pain Relevance 0

General Comments

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