INT92523

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Context Info
Confidence 0.63
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.15
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Homer1) cytoplasm (Homer1)
Anatomy Link Frequency
nucleus 1
Homer1 (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 2 99.66 Very High Very High Very High
parabrachial 1 98.76 Very High Very High Very High
tetrodotoxin 1 78.12 Quite High
antagonist 2 76.68 Quite High
medulla 1 75.00 Quite High
Intracerebroventricular 2 74.76 Quite High
anesthesia 2 71.16 Quite High
Hippocampus 9 70.40 Quite High
adenocard 2 65.72 Quite High
Pyramidal cell 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 91.28 High High
Anxiety Disorder 29 61.56 Quite High
Nociception 1 5.48 Low Low
Shock 15 5.00 Very Low Very Low Very Low
Convulsion 2 5.00 Very Low Very Low Very Low
Diphtheria 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This suggests that the short form of Vesl-1 plays a role in LTM formation when repeated reinforcement of the learning paradigm is lacking.
Phosphorylation (form) of Vesl-1
1) Confidence 0.63 Published 2009 Journal Mol Brain Section Body Doc Link PMC2663561 Disease Relevance 0.15 Pain Relevance 0.04
Regionally, CREB was dephosphorylated wherever immediate-early gene expression went up.
Phosphorylation (dephosphorylated) of immediate-early gene
2) Confidence 0.02 Published 2002 Journal Exp. Neurol. Section Abstract Doc Link 12009775 Disease Relevance 0 Pain Relevance 0.16
We suggest that N-methyl-D-aspartate receptors couple c-AMP to phosphorylation events and immediate early gene induction in the nucleus of striatal medium spiny neurons.
Phosphorylation (phosphorylation) of immediate early gene in nucleus associated with nmda receptor
3) Confidence 0.01 Published 2000 Journal Neuroscience Section Abstract Doc Link 11113310 Disease Relevance 0 Pain Relevance 0.33

General Comments

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