INT92544

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Context Info
Confidence 0.45
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.73
Pain Relevance 1.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hmox2) endoplasmic reticulum (Hmox2) plasma membrane (Hmox2)
Anatomy Link Frequency
neuronal 1
paw 1
spinal cord 1
Hmox2 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 9 100.00 Very High Very High Very High
COX2 3 100.00 Very High Very High Very High
cOX1 3 100.00 Very High Very High Very High
Spinal cord 12 99.92 Very High Very High Very High
Neuronal nitric oxide synthase 15 99.80 Very High Very High Very High
Central nervous system 3 98.08 Very High Very High Very High
Inflammation 12 95.92 Very High Very High Very High
Dorsal horn neuron 9 95.36 Very High Very High Very High
Disease Link Frequency Relevance Heat
INFLAMMATION 12 95.92 Very High Very High Very High
Nociception 3 95.72 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Localization and regulation of cyclo-oxygenase-1 and -2 and neuronal nitric oxide synthase in mouse spinal cord.
Localization (Localization) of cyclo-oxygenase-1 and -2 in spinal cord associated with cox1, spinal cord and neuronal nitric oxide synthase
1) Confidence 0.45 Published 2000 Journal Neuroscience Section Title Doc Link 11113358 Disease Relevance 0.24 Pain Relevance 0.81
The present immunohistochemical study details localization and regulation of cyclo-oxygenase-1 and -2 and neuronal nitric oxide synthase in lumbar spinal cord before and after induction of a painful paw inflammation in mice.
Localization (localization) of cyclo-oxygenase-1 and -2 in paw associated with pain, inflammation, spinal cord and neuronal nitric oxide synthase
2) Confidence 0.42 Published 2000 Journal Neuroscience Section Abstract Doc Link 11113358 Disease Relevance 0.25 Pain Relevance 0.49
Cyclo-oxygenase-2 was co-localized with neuronal nitric oxide synthase immunoreactivity in several neurons in superficial laminae of the dorsal horns and in the area surrounding the central canal.
Localization (co-localized) of Cyclo-oxygenase-2 in neuronal associated with neuronal nitric oxide synthase
3) Confidence 0.42 Published 2000 Journal Neuroscience Section Abstract Doc Link 11113358 Disease Relevance 0.23 Pain Relevance 0.57

General Comments

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