INT92591

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Context Info
Confidence 0.28
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IGF2) extracellular region (IGF2) carbohydrate metabolic process (IGF2)
Anatomy Link Frequency
Caco-2 2
IGF2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 62.64 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 1 91.84 High High
Cancer 1 80.48 Quite High
Colon Cancer 4 75.68 Quite High
INFLAMMATION 1 62.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also, the blockade of the PI3-kinase, that mediates the proliferative effect of IGF-I receptor in Caco-2 cells, inhibits IGF-II-dependent COX-2 up-regulation and PGE2 synthesis.
Negative_regulation (inhibits) of Positive_regulation (up-regulation) of IGF-II in Caco-2
1) Confidence 0.28 Published 2000 Journal Oncogene Section Abstract Doc Link 11114729 Disease Relevance 0.45 Pain Relevance 0.06

General Comments

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