INT92619

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Context Info
Confidence 0.48
First Reported 1999
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 2.32
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (LCT) plasma membrane (LCT) carbohydrate metabolic process (LCT)
LCT (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 1 71.08 Quite High
depression 1 69.00 Quite High
Inflammation 7 60.00 Quite High
Angina 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Somatostatin 2 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
epidural 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiovascular Disease 140 99.56 Very High Very High Very High
Toxicity 1 97.52 Very High Very High Very High
Pain 1 96.08 Very High Very High Very High
Sepsis 5 89.32 High High
Genetic Predisposition To Disease 3 86.00 High High
Lactose Intolerance 3 78.56 Quite High
Infection 5 75.04 Quite High
Malabsorption Syndromes 5 75.00 Quite High
Coronary Artery Disease 96 73.84 Quite High
Injury 10 72.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent reports have identified genetic polymorphisms that are closely associated with lactase persistence and nonpersistence phenotypes.
lactase Binding (associated) of
1) Confidence 0.48 Published 2004 Journal Am J Pharmacogenomics Section Abstract Doc Link 15287817 Disease Relevance 0.65 Pain Relevance 0.07
DESIGN: This was a randomized, prospective, controlled, open-label study comparing a new 25 mmol/L bicarbonate/15 mmol/L lactate with a standard 40 mmol/L lactate-buffered peritoneal dialysis solution (Lac) over a 12-month treatment period.
Lac Binding (comparing) of
2) Confidence 0.36 Published 2000 Journal Perit Dial Int Section Body Doc Link 11117242 Disease Relevance 0.10 Pain Relevance 0
Two of the genes we selected to this study, LCT and APOBEC2, have not been previously associated with molecular pathogenesis of cardiovascular disease.
LCT Binding (associated) of associated with cardiovascular disease
3) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2574036 Disease Relevance 0.59 Pain Relevance 0
We found association between LCT variants and both total and LDL cholesterol.
LCT Binding (association) of
4) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2574036 Disease Relevance 0.52 Pain Relevance 0
These are lipids with both LCT and MCT bonded to the glycerol backbone (Fig. 2).
LCT Binding (lipids) of
5) Confidence 0.08 Published 1999 Journal Crit Care Section Body Doc Link PMC137235 Disease Relevance 0.46 Pain Relevance 0.06

General Comments

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