INT92694

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Context Info
Confidence 0.31
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tgfb1, Col3a1) extracellular region (Tgfb1, Col3a1) proteinaceous extracellular matrix (Tgfb1, Col3a1)
enzyme binding (Tgfb1) cytoplasm (Tgfb1) cell proliferation (Tgfb1)
Anatomy Link Frequency
PSC 2
Tgfb1 (Mus musculus)
Col3a1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 3 100.00 Very High Very High Very High
Chronic pancreatitis 1 67.72 Quite High
Disease Link Frequency Relevance Heat
Fibrosis 4 100.00 Very High Very High Very High
Primary Sclerosing Cholangitis 3 100.00 Very High Very High Very High
Targeted Disruption 3 75.00 Quite High
Pancreatitis 1 67.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This confirms that TGF-beta1 mediates pancreatic fibrosis through activation of PSC and deposition of collagen type I and III at early time points.
TGF-beta1 Positive_regulation (mediates) of Positive_regulation (activation) of collagen type I and III in PSC associated with fibrosis and primary sclerosing cholangitis
1) Confidence 0.31 Published 2001 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 11123210 Disease Relevance 0.89 Pain Relevance 0.19

General Comments

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