INT92800

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Context Info
Confidence 0.37
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Arrb2, Oprm1) plasma membrane (Arrb2, Oprm1) transport (Arrb2)
nucleus (Arrb2) intracellular (Arrb2) signal transducer activity (Oprm1)
Arrb2 (Mus musculus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 3 100.00 Very High Very High Very High
Morphine 5 99.52 Very High Very High Very High
tolerance 5 99.16 Very High Very High Very High
addiction 3 98.44 Very High Very High Very High
Pain 2 97.04 Very High Very High Very High
opiate 1 93.48 High High
agonist 1 84.64 Quite High
Antinociceptive 2 67.44 Quite High
Physical dependence 1 65.28 Quite High
Disease Link Frequency Relevance Heat
Pain 2 97.04 Very High Very High Very High
Targeted Disruption 1 74.04 Quite High
Drug Dependence 1 65.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence.
beta-arrestin-2 Negative_regulation (desensitization) of Mu-opioid receptor associated with addiction, tolerance, opioid receptor and morphine
1) Confidence 0.37 Published 2000 Journal Nature Section Title Doc Link 11130073 Disease Relevance 0.33 Pain Relevance 1.24

General Comments

This test has worked.

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