INT92974

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Context Info
Confidence 0.32
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Galr1) mitochondrion (Creb1) plasma membrane (Galr1)
nucleus (Creb1) DNA binding (Creb1) transcription factor binding (Creb1)
Creb1 (Mus musculus)
Galr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Locus ceruleus 4 91.68 High High
opiate 4 90.24 High High
withdrawal 2 89.68 High High
analgesia 1 58.48 Quite High
Peripheral nervous system 1 53.48 Quite High
Neuropeptide 1 49.56 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gel shift and super-shift experiments demonstrate that the transcription factor CREB can bind to both sites and is likely to be responsible for the cAMP-mediated increase in GalR1 promoter activity.
CREB Regulation (responsible) of Positive_regulation (increase) of GalR1
1) Confidence 0.32 Published 2001 Journal J. Neurochem. Section Abstract Doc Link 11145992 Disease Relevance 0 Pain Relevance 0.57

General Comments

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