INT93004

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.47
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.93
Pain Relevance 1.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VCAM1) aging (VCAM1) cell adhesion (VCAM1)
plasma membrane (VCAM1)
Anatomy Link Frequency
blood vessels 4
skin 2
VCAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 1 99.98 Very High Very High Very High
Neuropeptide 3 99.46 Very High Very High Very High
Central nervous system 30 97.76 Very High Very High Very High
Inflammation 26 95.00 High High
Multiple sclerosis 280 91.08 High High
substance P 8 88.96 High High
metalloproteinase 2 87.44 High High
cytokine 15 85.36 High High
Inflammatory response 6 72.64 Quite High
chemokine 4 67.52 Quite High
Disease Link Frequency Relevance Heat
Adhesions 34 100.00 Very High Very High Very High
Pre-eclampsia 46 99.56 Very High Very High Very High
INFLAMMATION 34 95.00 High High
Demyelinating Disease 308 91.08 High High
Necrosis 4 90.68 High High
Cancer 8 90.32 High High
Bacterial Infection 2 63.12 Quite High
Influenza Virus Infection 2 56.56 Quite High
Measles 4 56.12 Quite High
Autoimmune Disease 7 48.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results indicate that the topical cutaneous application of the neuropeptide-releasing agent capsaicin resulted in increased ICAM-1 and VCAM-1 immunostaining of microvascular cells in the skin of human volunteers.
Positive_regulation (resulted) of Positive_regulation (increased) of VCAM-1 in skin associated with qutenza and neuropeptide
1) Confidence 0.47 Published 2000 Journal J. Investig. Dermatol. Symp. Proc. Section Abstract Doc Link 11147679 Disease Relevance 0.45 Pain Relevance 0.67
Our results indicated that circulating sVCAM-1 levels were significantly increased in severe preeclampsia compared with mild preeclampsia or normal pregnancy.
Positive_regulation (increased) of Positive_regulation (circulating) of sVCAM-1 associated with pre-eclampsia
2) Confidence 0.43 Published 2004 Journal Journal of Korean Medical Science Section Body Doc Link PMC2816332 Disease Relevance 0.83 Pain Relevance 0.09
Paramount events in the periphery consist of T-cell activation, tethering, rolling, and adhesion, facilitated by integrin expression on activated T cells and interaction with its upregulated ligand vascular cellular adhesion molecule-1 (VCAM-1), expressed on the endothelium of blood vessels of the CNS.
Positive_regulation (activated) of Positive_regulation (upregulated) of VCAM-1 in blood vessels associated with central nervous system and adhesions
3) Confidence 0.11 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2998807 Disease Relevance 0.83 Pain Relevance 0.45
Paramount events in the periphery consist of T-cell activation, tethering, rolling, and adhesion, facilitated by integrin expression on activated T cells and interaction with its upregulated ligand vascular cellular adhesion molecule-1 (VCAM-1), expressed on the endothelium of blood vessels of the CNS.
Positive_regulation (activated) of Positive_regulation (upregulated) of vascular cellular adhesion molecule-1 in blood vessels associated with central nervous system and adhesions
4) Confidence 0.11 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2998807 Disease Relevance 0.82 Pain Relevance 0.45

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox