INT93044

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Context Info
Confidence 0.58
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.17
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Csrp1)
Anatomy Link Frequency
blood 2
joints 2
Csrp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 1 100.00 Very High Very High Very High
Inflammation 4 99.48 Very High Very High Very High
Inflammatory marker 1 98.78 Very High Very High Very High
Migraine 11 97.60 Very High Very High Very High
rheumatoid arthritis 4 87.96 High High
Disease Link Frequency Relevance Heat
Adhesions 1 100.00 Very High Very High Very High
INFLAMMATION 4 99.48 Very High Very High Very High
Stress 1 98.52 Very High Very High Very High
Thrombosis 1 98.08 Very High Very High Very High
Headache 11 97.60 Very High Very High Very High
Body Weight 1 97.20 Very High Very High Very High
Hypertension 1 96.68 Very High Very High Very High
Hyperlipidemia 1 95.84 Very High Very High Very High
Stroke 1 92.72 High High
Coronary Artery Disease 1 92.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients in the surgically treated groups (groups A and B) showed a significant reduction in the number of swollen and painful joints and in their ESR and serum CRP levels, and this effect was maintained for at least 3 years.
Negative_regulation (reduction) of Gene_expression (levels) of CRP in joints associated with pain
1) Confidence 0.58 Published 2000 Journal Int Orthop Section Abstract Doc Link 11153450 Disease Relevance 0.39 Pain Relevance 0.25
Several studies indicate that migraine is associated with special pattern of inflammatory markers and some adverse vascular risk factors including: increased levels of CRP, ILs, TNF-alpha and adhesion molecules which are markers of systemic inflammation, oxidative stress and thrombosis, increased body weight, high blood pressure, hypercholesterolemia, impaired insulin sensitivity, high homocysteine levels, stroke and coronary heart disease.
Negative_regulation (markers) of Gene_expression (levels) of CRP in blood associated with stress, coronary artery disease, body weight, stroke, migraine, thrombosis, inflammation, inflammatory marker, hypertension, hyperlipidemia and adhesions
2) Confidence 0.06 Published 2009 Journal Atherosclerosis Section Abstract Doc Link 19054516 Disease Relevance 1.78 Pain Relevance 0.78

General Comments

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