INT9311

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Context Info
Confidence 0.60
First Reported 1992
Last Reported 2010
Negated 1
Speculated 4
Reported most in Abstract
Documents 13
Total Number 17
Disease Relevance 6.41
Pain Relevance 6.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Ssr1)
Anatomy Link Frequency
sympathetic 5
autonomic 1
bowel 1
gracile nucleus 1
Ssr1 (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 6 100.00 Very High Very High Very High
sSRI 4 100.00 Very High Very High Very High
b2 receptor 2 100.00 Very High Very High Very High
Rsd 18 99.60 Very High Very High Very High
antagonist 10 99.50 Very High Very High Very High
opioid receptor 5 99.26 Very High Very High Very High
spastic colon 12 98.96 Very High Very High Very High
electroacupuncture 118 98.46 Very High Very High Very High
carpal tunnel syndrome 12 98.36 Very High Very High Very High
Sciatica 3 97.92 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 6 100.00 Very High Very High Very High
Reflex Sympathetic Dystrophy 20 99.60 Very High Very High Very High
Nerve Root Compression 6 99.44 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

10 98.96 Very High Very High Very High
Carpal Tunnel Syndrome 12 98.36 Very High Very High Very High
Targeted Disruption 4 96.44 Very High Very High Very High
Constipation 3 95.52 Very High Very High Very High
Diarrhoea 2 90.88 High High
Pulmonary Disease 7 88.96 High High
Sleep Disorders 7 85.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To test for the contribution of the 5-HT(1B) receptor subtype in mediating the effects of fluoxetine, a selective serotonin reuptake inhibitor (SSRI), we used intracerebral in vivo microdialysis in awake, freely moving 5-HT(1B) receptor knock-out mice.
Regulation (effects) of SSRI associated with targeted disruption, ssri and fluoxetine
1) Confidence 0.60 Published 2002 Journal Eur. J. Pharmacol. Section Abstract Doc Link 12044798 Disease Relevance 0.38 Pain Relevance 0.66
The effect of 30-min tourniquet ischaemia (Bier's block) on the antidromic homolateral left median nerve sensory potential (SP) and on the bilateral sympathetic skin response (SSR) was studied in 6 healthy volunteers.
Regulation (effect) of SSR in sympathetic associated with cv unclassified under development
2) Confidence 0.23 Published 1992 Journal Pain Section Abstract Doc Link 1408313 Disease Relevance 0.45 Pain Relevance 0.13
When using this technique the SSR is not significantly altered in L5 and S1 radiculopathies.
Neg (not) Regulation (altered) of SSR associated with nerve root compression
3) Confidence 0.23 Published 1993 Journal Electromyogr Clin Neurophysiol Section Abstract Doc Link 8383595 Disease Relevance 0.48 Pain Relevance 0.27
Thus, a change in the SSR status might be useful for identifying patients who can successfully wean even after prolonged CVU admission.
Regulation (change) of SSR
4) Confidence 0.17 Published 2003 Journal BMC Pulm Med Section Body Doc Link PMC305355 Disease Relevance 0.53 Pain Relevance 0.04
The combined effect of SSR and image reconstruction improves the CNR in all 10 datasets for HbO2 and HbT, and nine of 10 datasets for HbR.
Regulation (effect) of SSR
5) Confidence 0.08 Published 2010 Journal Frontiers in Neuroenergetics Section Body Doc Link PMC2914577 Disease Relevance 0 Pain Relevance 0.11
Increasing evidence has suggested that both sympathetic activity and stimulation-induced SSR are differentially controlled in an organ-specific and activity-dependent manner.
Regulation (controlled) of SSR in sympathetic
6) Confidence 0.07 Published 2009 Journal Chin J Physiol Section Abstract Doc Link 20359125 Disease Relevance 0.42 Pain Relevance 1.13
Before surgery, anomalies of M3 SSR were found in 8 hands (40%): M3 SSR was absent in 1 hand; and the M3c/M3 SSR largest area ratio was abnormal in 7 hands, 3 of which also had abnormal mean differences between M3 and M3c SSR latencies.
Regulation (abnormal) of SSR
7) Confidence 0.05 Published 2001 Journal Muscle Nerve Section Abstract Doc Link 11150978 Disease Relevance 0.43 Pain Relevance 0.43
We conclude that NO in the Gr plays an inhibitory role in the central cardiovascular control through SSR regulation.
Regulation (regulation) of SSR
8) Confidence 0.04 Published 2002 Journal Brain Res. Section Abstract Doc Link 12470869 Disease Relevance 0.13 Pain Relevance 0.06
IBS patients, despite their bowel habit, showed normal SSR response.
Regulation (response) of SSR in bowel associated with spastic colon
9) Confidence 0.04 Published 1998 Journal Dig. Dis. Sci. Section Abstract Doc Link 9724171 Disease Relevance 0.85 Pain Relevance 0.94
Although the functional purpose for the transganglionic and/or transsynaptic up-regulation of nNOS in the gracile nucleus requires investigation, the results suggest that EA-induced nNOS-NO in the gracile nucleus may participate in central autonomic regulation of somatosympathetic reflex (SSR) activities, which contribute to the therapeutic effects of acupuncture.
Regulation (regulation) of SSR in autonomic associated with acupuncture and electroacupuncture
10) Confidence 0.02 Published 2004 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC442119 Disease Relevance 0.14 Pain Relevance 0.28
However, as there is no consensus in the literature for the clinical criteria to diagnose RSD, it is not yet possible to determine the final diagnostic value of SSR for the diagnoses of RSD.
Spec (determine) Regulation (value) of SSR associated with rsd
11) Confidence 0.02 Published 1995 Journal Clin. Auton. Res. Section Abstract Doc Link 8520215 Disease Relevance 0.78 Pain Relevance 0.55
The aim of this study was to determine the sensitivity of sympathetic skin response (SSR) in evaluating autonomic involvement in carpal tunnel syndrome (CTS) while simultaneously showing the axonal loss by motor unit number estimation (MUNE).
Spec (determine) Regulation (sensitivity) of SSR in sympathetic associated with carpal tunnel syndrome
12) Confidence 0.02 Published 2007 Journal J Clin Neurophysiol Section Abstract Doc Link 17277581 Disease Relevance 0.27 Pain Relevance 0.27
The aim of the study was to verify the diagnostic value of SSR in patients with reflex sympathetic dystrophy (RSD).
Regulation (value) of SSR in sympathetic associated with rsd
13) Confidence 0.02 Published 1995 Journal Clin. Auton. Res. Section Abstract Doc Link 8520215 Disease Relevance 0.50 Pain Relevance 0.36
We hypothesize that NO in the gracile nucleus plays an inhibitory role in central cardiovascular control through SSR regulation (Fig. 1).
Regulation (regulation) of SSR in gracile nucleus
14) Confidence 0.01 Published 2004 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC442119 Disease Relevance 0.05 Pain Relevance 0.35
Capsaicin pretreatment (40 mg/kg/day, 3 days) abolished the effects of the opioid receptor antagonists, but did not change the effect of kinin B2 receptor blockade on the SSR.
Regulation (effect) of SSR associated with qutenza, antagonist, b2 receptor and opioid receptor
15) Confidence 0.01 Published 2005 Journal Peptides Section Abstract Doc Link 15908043 Disease Relevance 0.07 Pain Relevance 0.81
UNLABELLED: The aim of the present study was to examine the value of the sympathetic skin response (SSR) in the diagnosis of reflex sympathetic dystrophy (RSD).
Spec (examine) Regulation (value) of SSR in sympathetic associated with rsd and reflex sympathetic dystrophy
16) Confidence 0.01 Published 1996 Journal Schmerz Section Abstract Doc Link 12799869 Disease Relevance 0.27 Pain Relevance 0.17
However, as there is no consensus on the clinical criteria for diagnosis of RSD, it is also not possible to determine the diagnostic value of SSR in the diagnosis of RSD.


Spec (determine) Regulation (value) of SSR
17) Confidence 0.01 Published 1996 Journal Schmerz Section Body Doc Link 12799869 Disease Relevance 0 Pain Relevance 0

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