INT93198

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.62
First Reported 2001
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 7
Total Number 8
Disease Relevance 1.96
Pain Relevance 3.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ASIC1) transport (ASIC1) plasma membrane (ASIC1)
Anatomy Link Frequency
oligodendroglia 3
chest 1
ASIC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
ASIC 79 100.00 Very High Very High Very High
ischemia 5 100.00 Very High Very High Very High
Angina 2 100.00 Very High Very High Very High
Inflammation 8 99.24 Very High Very High Very High
Serotonin 4 98.96 Very High Very High Very High
imagery 6 98.52 Very High Very High Very High
Action potential 2 98.32 Very High Very High Very High
Hyperalgesia 2 92.04 High High
Pain 6 91.36 High High
bradykinin 2 89.84 High High
Disease Link Frequency Relevance Heat
Angina 2 100.00 Very High Very High Very High
Coronary Artery Disease 2 100.00 Very High Very High Very High
Status Epilepticus 3 99.30 Very High Very High Very High
INFLAMMATION 8 99.24 Very High Very High Very High
Acidosis 4 96.12 Very High Very High Very High
Hyperalgesia 2 92.04 High High
Pain 6 91.36 High High
Death 1 87.84 High High
Epilepsy 1 75.00 Quite High
Ageusia 32 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finding no transcripts for ASIC1a we used RT-PCR to search for transcripts for ASIC1?
Neg (no) Transcription (transcripts) of ASIC1a
1) Confidence 0.62 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2754526 Disease Relevance 0 Pain Relevance 0.04
Finding no transcripts for ASIC1a we used RT-PCR to search for transcripts for ASIC1?
Transcription (transcripts) of ASIC1
2) Confidence 0.62 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2754526 Disease Relevance 0 Pain Relevance 0.07
ASIC transcripts were also detected in brain white matter, and ASIC1a protein expression was detected in white matter oligodendroglia.
Transcription (detected) of ASIC in oligodendroglia associated with asic
3) Confidence 0.52 Published 2008 Journal Glia Section Abstract Doc Link 18452213 Disease Relevance 0.07 Pain Relevance 0.37
ASIC transcripts were also detected in brain white matter, and ASIC1a protein expression was detected in white matter oligodendroglia.
Transcription (detected) of ASIC1a in oligodendroglia associated with asic
4) Confidence 0.52 Published 2008 Journal Glia Section Abstract Doc Link 18452213 Disease Relevance 0.07 Pain Relevance 0.37
ASIC1a, ASIC2a, and ASIC4 mRNAs were expressed in cultured rat OLC, with steady-state levels of each of these mRNAs several-fold higher in oligodendroglial progenitors than in mature oligodendroglia.
Transcription (expressed) of ASIC1a in oligodendroglia
5) Confidence 0.52 Published 2008 Journal Glia Section Abstract Doc Link 18452213 Disease Relevance 0.08 Pain Relevance 0.35
An analysis of the promoter region of the ASIC3 encoding gene, an ASIC specifically expressed in sensory neurons and associated with chest pain that accompanies cardiac ischemia, reveals that gene transcription is controlled by NGF and serotonin.
Transcription (transcription) of ASIC in chest associated with angina, coronary artery disease, ischemia, serotonin and asic
6) Confidence 0.04 Published 2002 Journal J. Neurosci. Section Abstract Doc Link 12486159 Disease Relevance 0.57 Pain Relevance 0.81
We had previously shown that ASIC transcript levels were increased in inflammatory conditions in vivo.
Transcription (levels) of ASIC associated with inflammation and asic
7) Confidence 0.04 Published 2002 Journal J. Neurosci. Section Abstract Doc Link 12486159 Disease Relevance 0.46 Pain Relevance 0.78
In animals treated with pilocarpine (380 mg/kg) to induce SE, we observed a marked decrease of ASIC2b mRNA levels in all hippocampal areas and of ASIC1a mRNA levels in the CA1-2 fields.
Transcription (levels) of ASIC2b associated with status epilepticus
8) Confidence 0.00 Published 2001 Journal Neurobiol. Dis. Section Abstract Doc Link 11162239 Disease Relevance 0.71 Pain Relevance 0.24

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox